Annual Meeting of the NCI Cohort Consortium (Abstract Submission)

Abstract Submission

Lightning Talk Abstract Submissions: If you are submitting a Lightning Talk these can be presented in-person or virtual on November 14, please see the Agenda page for the session time. Lightning talks can be on any new ideas, works in progress or completed work. Preference will be given to Early Career Scientists. Abstracts should include a Background, Methods, Results, and Conclusion/Discussion.

Abstract submission is due by September 13, 11:59 PM ET.

All submitters will be contacted regarding their presentation status approximately 2 weeks after the submission deadline.

OMB No.: 0925-0740
Expiration Date: 9/30/2025

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Submission information

Submission Number: 7

Submission ID: 127364

Submission UUID: b8a6af7b-6785-49bf-afb2-3259de85ae1f

Submission URI: /egrp/cohortconsortium/abstracts

Submission Update: /egrp/cohortconsortium/abstracts?token=n8KkGmbqnYr2fSkFo8EsZc4WUAIFeCq8tyGeEZKX1YA

Created: Wed, 09/11/2024 - 16:19

Completed: Wed, 09/11/2024 - 16:19

Changed: Wed, 09/11/2024 - 16:19

Remote IP address: 10.208.28.69

Submitted by: Anonymous

Language: English

Is draft: No

Webform: Cohort 2024 (Abstracts Submission)

Submitted to: Annual Meeting of the NCI Cohort Consortium (Abstract Submission)

Lightning Talks Abstract

The abstract for Lightning Talk should be 250-words or less and use the following headers: Background, Methods, Results, and Conclusion/Discussion.

Presenter's First Name:

Presenter's Last Name:

Title (eg: professor, assistant professor, chair, etc):

Degree(s)

Contact Email:

Please provide a contact email for conference organizers to reach you.

Organization:

Project Title:

Max 250 characters, use Title Case

Additional Authors

Please use the following formatting for these degrees: M.D. Ph.D. MPH

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	First Name	Middle Initial	Last Name	Degree(s)	Organization	Item weight

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Abstract:

Colorectal cancer (CRC) is the second overall leading cause of cancer death in the United States. CRC poses a disproportionate burden among Black individuals, who experience substantially higher recurrence and mortality rates. In the ColoCare cohort, Black CRC survivors had higher risks for mortality, poorer disease-free survival, and differences in potentially clinically actional tumor mutational status. Approaches to improve survivorship outcomes among Black CRC survivors are urgently needed; however, most existing prospective survivorship cohort studies have limited ability to adequately assess potentially actionable drivers of cancer outcomes among this population due to small sample sizes (particularly among ethnic subgroups). To address this gap, we propose to create a forum for collaboration across survivorship cohorts to facilitate deep analyses of the multidimensional aspects of tumor biology and outcomes among Black CRC survivors.  To do this, we propose to pool data from Black CRC survivors in existing prospective cohorts to assess the multi-level drivers of survivorship outcomes including 1) tumor molecular profiles; 2) the local and peripheral immune system; 3) intervenable lifestyle exposures; 4) the gastrointestinal microbiome; and 5) social drivers of health. We will leverage the resources of multiple cohorts–including the ColoCare study, the Cancer Genome Atlas, the Southern Community Cohort, the African Caribbean Consortium, and the Detroit Research on Cancer Survivors study, and the Women’s Health Initiative-Life and Longevity After Cancer study– with biospecimens and data collected at diagnosis and afterward. Integration of these cohorts will allow for powerful analyses of predictors of outcomes among Black CRC survivors.