NCI Drug Development Workshop (Materials)

Materials

The recording of each session will be posted within a week of its completion.

The Developmental Therapeutics Program (DTP) offers drug discovery and development resources and services to the research community. Visit https://dtp.cancer.gov/ for more information.

The Division of Cancer Treatment and Diagnosis (DCTD) is seeking project proposals for viral vector and cell therapy production at NCI.

 

Session I - July 23, 2021
Recording link:

https://nci.rev.vbrick.com/#/videos/117154fc-1fac-46eb-bf35-3f4ea692111b

Presentation:

NCI Workshop Session I Grand Overview
Key milestones in drug development and components of an IND-package

Session II - July 30, 2021
Recording link:

https://nci.rev.vbrick.com/sharevideo/52da8ce9-9635-4f2b-907f-e230cea5eeb4

Presentation:

Pre-clinical Proof of Concept: Establishing Activity, Bioavailability, and Associated Effect, in Cancer Relevant Models
Preclinical pharmacology in IND-enabling studies and clinical pharmacology in clinical protocol development

Session III - August 6, 2021
Recording link:

https://nci.rev.vbrick.com/sharevideo/040958fd-d596-460f-af17-14719fa2eee2

Presentation:

Preliminary and IND-directed toxicology studies
Assays and endpoints for toxicology studies to assess immune-related adverse events

Session IV - August 20, 2021
Recording link:

https://nci.rev.vbrick.com/sharevideo/1980c808-bd8a-44c9-96b2-863021095e98

Presentation:

Assays and Analytical Methods Needed for API Release
Challenges in Early Phase API Scale Up
The Role of Occam's Razor in Formulation Design