Childhood Cancer Data Initiative Annual Symposium (Abstract Registration): Submission #59

Submission information
Submission Number: 59
Submission ID: 150490
Submission UUID: a536d34d-7419-40b2-88d3-29ab3407dfe6
Submission URI: /nci/ccdisymposium/abstract
Submission Update: /nci/ccdisymposium/abstract?token=Uwvjh5JqrOn2m_MCmD2kULy9GGUkcw6iRG5d0Bq9TQs
Created: Mon, 09/01/2025 - 20:30
Completed: Mon, 09/01/2025 - 21:17
Changed: Mon, 09/01/2025 - 21:17
Remote IP address: 10.208.28.30
Submitted by: Anonymous
Language: English
Is draft: No
Webform: Childhood Cancer Data Initiative Annual Symposium (Abstracts Submission)
Submitted to: Childhood Cancer Data Initiative Annual Symposium (Abstract Registration)
serial: '59'
sid: '150490'
uuid: a536d34d-7419-40b2-88d3-29ab3407dfe6
uri: /nci/ccdisymposium/abstract
created: '1756773027'
completed: '1756775859'
changed: '1756775859'
in_draft: '0'
current_page: ''
remote_addr: 10.208.28.30
uid: '0'
langcode: en
webform_id: ccdi_symposium_abstract
entity_type: node
entity_id: '2139'
locked: '0'
sticky: '0'
notes: ''
metatag: meta
data:
  authors_:
    - add_author_degree: M.S.
      add_author_first_name: Ritika
      add_author_last_name: Kundra
      add_author_middle: ''
      add_author_organization: MSK
    - add_author_degree: M.S.
      add_author_first_name: Rima
      add_author_last_name: AlHamad
      add_author_middle: ''
      add_author_organization: MSK
    - add_author_degree: M.S.
      add_author_first_name: Robert
      add_author_last_name: Sheridan
      add_author_middle: ''
      add_author_organization: MSK
    - add_author_degree: M.S.
      add_author_first_name: Manda
      add_author_last_name: Wilson
      add_author_middle: ''
      add_author_organization: MSK
    - add_author_degree: M.S.
      add_author_first_name: Avery
      add_author_last_name: Wang
      add_author_middle: ''
      add_author_organization: MSK
    - add_author_degree: B.S.
      add_author_first_name: Benjamin
      add_author_last_name: Preiser
      add_author_middle: ''
      add_author_organization: MSK
    - add_author_degree: M.S.
      add_author_first_name: Benjamin
      add_author_last_name: Gross
      add_author_middle: ''
      add_author_organization: MSK
    - add_author_degree: B.S.
      add_author_first_name: Kelly
      add_author_last_name: Cavender
      add_author_middle: ''
      add_author_organization: MSK
    - add_author_degree: Ph.D.
      add_author_first_name: Sarah
      add_author_last_name: Suehnholz
      add_author_middle: P
      add_author_organization: MSK
    - add_author_degree: M.S.
      add_author_first_name: Ramyasree
      add_author_last_name: Madupuri
      add_author_middle: ''
      add_author_organization: MSK
    - add_author_degree: M.S.
      add_author_first_name: Baby
      add_author_last_name: Satravada
      add_author_middle: A
      add_author_organization: MSK
    - add_author_degree: M.D.
      add_author_first_name: Neerav
      add_author_last_name: Shukla
      add_author_middle: 'N'
      add_author_organization: MSK
    - add_author_degree: B.A.
      add_author_first_name: Stephanie
      add_author_last_name: Suser
      add_author_middle: ''
      add_author_organization: MSK
    - add_author_degree: M.D.
      add_author_first_name: Mark
      add_author_last_name: Ewalt
      add_author_middle: ''
      add_author_organization: MSK
    - add_author_degree: 'M.D., Ph.D.'
      add_author_first_name: Tejus
      add_author_last_name: Bale
      add_author_middle: ''
      add_author_organization: MSK
    - add_author_degree: M.D.
      add_author_first_name: Maria
      add_author_last_name: Arcila
      add_author_middle: E
      add_author_organization: MSK
    - add_author_degree: M.S.
      add_author_first_name: Aijaz
      add_author_last_name: Syed
      add_author_middle: ''
      add_author_organization: MSK
    - add_author_degree: M.S.
      add_author_first_name: Mihir
      add_author_last_name: Kavatkar
      add_author_middle: ''
      add_author_organization: MSK
    - add_author_degree: Ph.D.
      add_author_first_name: Tali
      add_author_last_name: Mazor
      add_author_middle: ''
      add_author_organization: DFCI
    - add_author_degree: Ph.D.
      add_author_first_name: Ethan
      add_author_last_name: Cerami
      add_author_middle: ''
      add_author_organization: DFCI
    - add_author_degree: 'M.D., Ph.D.'
      add_author_first_name: Justin
      add_author_last_name: Jee
      add_author_middle: ''
      add_author_organization: MSK
    - add_author_degree: Ph.D.
      add_author_first_name: Christopher
      add_author_last_name: Fong
      add_author_middle: ''
      add_author_organization: MSK
    - add_author_degree: Ph.D.
      add_author_first_name: Michele
      add_author_last_name: Waters
      add_author_middle: ''
      add_author_organization: MSK
    - add_author_degree: Ph.D.
      add_author_first_name: Michael
      add_author_last_name: Berger
      add_author_middle: F
      add_author_organization: MSK
    - add_author_degree: Ph.D.
      add_author_first_name: Debyani
      add_author_last_name: Chakravarty
      add_author_middle: ''
      add_author_organization: MSK
    - add_author_degree: 'M.D., F.A.C.P.'
      add_author_first_name: Ingo
      add_author_last_name: Mellinghoff
      add_author_middle: K
      add_author_organization: MSK
    - add_author_degree: M.D.
      add_author_first_name: David
      add_author_last_name: Solit
      add_author_middle: B
      add_author_organization: MSK
    - add_author_degree: Ph.D.
      add_author_first_name: JianJiong
      add_author_last_name: Gao
      add_author_middle: ''
      add_author_organization: MSK
    - add_author_degree: Ph.D.
      add_author_first_name: Nikolaus
      add_author_last_name: Schultz
      add_author_middle: ''
      add_author_organization: MSK
  abstract: |-
    OncoTree is an open source, publicly accessible, community driven cancer classification system developed by Memorial Sloan Kettering Cancer Center and maintained by a cross-institutional committee of oncologists, pathologists, scientists, and engineers (OncoTree committee). Accessible through an intuitive web interface and API, OncoTree provides a structured hierarchical framework that standardizes cancer types, thereby supporting accurate diagnosis, therapeutic decision making, and data harmonization. Since its inception, OncoTree has grown to include over 900 tumor types, mapped to external terminologies such as NCI Thesaurus and UMLS, and is updated to align with standards like the World Health Organization (WHO) classification of tumors. All updates are publicly released with versioning, mapping tools, and detailed documentation to ensure transparency and reproducibility.

    Initially focused on adult malignancies, OncoTree is now undergoing concentrated efforts to expand and refine its pediatric classification nodes. Pediatric cancers are biologically and clinically distinct from adult tumors, presenting unique challenges for classification. The pediatric extension of OncoTree aims to comprehensively represent childhood malignancies by incorporating WHO pediatric classifications, capturing rare and developmentally driven tumor entities, and restructuring ontology branches to better reflect pediatric tumor biology. This effort includes mapping diagnoses across ontology versions and external terminologies, identifying coverage gaps, and implementing systematic revisions under the governance of the OncoTree committee.

    With clear documentation with release notes, source references, and support tools, this pediatric expansion will deliver a well-organized, transparent framework that improves the consistency of tumor classification, facilitates cross-study analyses, and strengthens the evidence base for clinical decision-making in childhood cancer care.
  abstract_title_: 'Pediatric Extension of OncoTree: An Open-Source, Cancer Classification System'
  email_address_: kundrar@mskcc.org
  institution_: 'Memorial Sloan Kettering'
  presenting_author_: 'Ritika Kundra'