Childhood Cancer Data Initiative Annual Symposium (Abstract Registration): Submission #42

Abstract Submission for Poster Presentation
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Abstract Title:: Childhood Cancer Data Initiative Federation API: Integrating Data Across Pediatric Cancer Institutions
Abstract::
While advances have been made in pediatric cancer treatments, an ongoing challenge is improving outcomes for patients with rare cancer subtypes as well as patients with refractory or recurrent disease.  A continuing barrier is the siloing of data across institutions, preventing researchers from assembling the large cohorts necessary to study cancer mechanisms and develop novel therapies.  To address this issue, the NCI’s Childhood Cancer Data Initiative (CCDI) developed the CCDI Federation API in 2022, creating a platform that aggregates and integrates clinical and research data from multiple pediatric cancer institutions.  Developed in collaboration with Children’s Hospital of Philadelphia, Pediatric Cancer Data Commons, St. Jude Children’s Research Hospital, and Treehouse Childhood Cancer Initiative, the Federation API was designed to be easily integrated into other NCI resources and includes detailed implementation guides for new participating institutions.  The Federation API empowers users to discover, access, and visualize data on hundreds of thousands of samples from thousands of patients, accelerating novel scientific discoveries and enhancing data access for researchers, clinicians, patients, and families.

Abstract:: {Empty}
Authors::
1. First Name: Subhashini
   Last Name: Jagu
   Degree(s): Ph.D.
   Organization: National Cancer Institute
2. First Name: Holly
   Middle Initial: C
   Last Name: Beale
   Degree(s): Ph.D.
   Organization: University of California, Santa Cruz
3. First Name: Ellen
   Middle Initial: T
   Last Name: Kephart
   Degree(s): B.S.
   Organization: University of California, Santa Cruz
4. First Name: Olena
   Middle Initial: M
   Last Name: Vaske
   Degree(s): Ph.D.
   Organization: University of California, Santa Cruz
5. First Name: Melissa
   Middle Initial: S
   Last Name: Cline
   Degree(s): Ph.D.
   Organization: University of California, Santa Cruz
6. First Name: Jingchun
   Last Name: Zhu
   Degree(s): Ph.D.
   Organization: University of California, Santa Cruz
7. First Name: Mary
   Middle Initial: J
   Last Name: Goldman
   Organization: University of California, Santa Cruz
8. First Name: Brian
   Last Name: Craft
   Organization: University of California, Santa Cruz
9. First Name: Allison
   Middle Initial: P
   Last Name: Heath
   Degree(s): Ph.D.
   Organization: Children's Hospital of Philadelphia
10. First Name: Hannah
    Middle Initial: R
    Last Name: Calkins
    Degree(s): M.S.
    Organization: Children's Hospital of Philadelphia
11. First Name: William
    Middle Initial: N
    Last Name: Khan
    Degree(s): B.S.
    Organization: Children's Hospital of Philadelphia
12. First Name: Xu
    Last Name: Zhu
    Degree(s): M.S.
    Organization: Children's Hospital of Philadelphia
13. First Name: Christopher
    Middle Initial: M
    Last Name: Nemarich
    Degree(s): M.A.
    Organization: Children's Hospital of Philadelphia
14. First Name: Jinghui
    Last Name: Zhang
    Degree(s): Ph.D.
    Organization: St. Jude Children's Research Hospital
15. First Name: Michael
    Last Name: Rusch
    Degree(s): M.S.
    Organization: St. Jude Children's Research Hospital
16. First Name: Clay
    Last Name: McLeod
    Degree(s): M.S.
    Organization: St. Jude Children's Research Hospital
17. First Name: Stephanie
    Last Name: Sandor
    Degree(s): M.S.
    Organization: St. Jude Children's Research Hospital
18. First Name: Jobin
    Middle Initial: Jacob
    Last Name: Sunny
    Degree(s): M.S.
    Organization: St. Jude Children's Research Hospital
19. First Name: Delaram
    Last Name: Rahbarinia
    Degree(s): M.S.
    Organization: St. Jude Children's Research Hospital
20. First Name: Kevin
    Last Name: Benton
    Degree(s): M.S.
    Organization: St. Jude Children's Research Hospital
21. First Name: Jake
    Last Name: Noble
    Degree(s): B.A.
    Organization: St. Jude Children's Research Hospital
22. First Name: Samuel
    Middle Initial: L
    Last Name: Volchenboum
    Degree(s): M.D., Ph.D.
    Organization: University of Chicago, Department of Pediatrics
23. First Name: Luca
    Last Name: Graglia
    Degree(s): M.S.
    Organization: University of Chicago, Department of Pediatrics
24. First Name: Michael
    Middle Initial: T
    Last Name: Watkins
    Degree(s): Ph.D.
    Organization: University of Chicago, Department of Pediatrics
25. First Name: Brian
    Middle Initial: T
    Last Name: Furner
    Degree(s): M.S.
    Organization: University of Chicago, Department of Pediatrics
26. First Name: Lydia
    Last Name: Rogers
    Degree(s): MBA
    Organization: Frederick National Laboratory for Cancer Research
27. First Name: Natalia
    Last Name: Asafieva
    Degree(s): Ph.D.
    Organization: Frederick National Laboratory for Cancer Research
28. First Name: Patrick
    Last Name: Dunn
    Degree(s): Ph.D.
    Organization: Frederick National Laboratory for Cancer Research
29. First Name: Mark
    Last Name: Cunningham
    Degree(s): M.A.
    Organization: Frederick National Laboratory for Cancer Research
30. First Name: Janisha
    Last Name: Patel
    Degree(s): M.S.
    Organization: Frederick National Laboratory for Cancer Research

Presenting Author:: A. Geoffrey Lyle
Institution:: University of California, Santa Cruz
Email Address:: aglyle@ucsc.edu