| Actv |
PI Name(s) All |
Title |
|---|
| R33 |
TEWARI, MUNEESH (contact); WALTER, NILS G |
Optimization and Validation of Single-Molecule Kinetic Fingerprinting Technology for Rapid, Ultra-Specific Detection of Cancer Mutations |
|---|
| R33 |
KONRY, TANIA TALI (contact); EVENS, ANDREW M; HUANG, TONY JUN |
Determining treatment sensitivity in B cell lymphoma by novel microfluidics-based NK cell immunogenicity platform |
|---|
| R21 |
NAEGLE, KRISTEN M |
A molecular toolkit for the production of tyrosine phosphorylated proteins |
|---|
| R21 |
NECHAEV, SERGEI |
Transcriptome profiling of highly degraded specimens through global analysis of short RNA fragments. |
|---|
| R21 |
BROCK, AMY |
High resolution cell lineage tracking and isolation |
|---|
| R21 |
PAULOVICH, AMANDA G |
Validation of a disposable biospecimen collection system with integral refrigeration for preserving the phosphoproteome |
|---|
| R33 |
WANG, YINGXIAO |
Multiplex FRET Imaging of Kinase-Epigenome Interregulations in Live Cancer Cells |
|---|
| R33 |
IBRAHIM, YEHIA |
High Resolution High Throughput Proteomics Platform for Cancer Research |
|---|
| R21 |
MALMSTADT, NOAH (contact); ROBERTS, RICHARD W |
A Target-Directed Reagent Pipeline via Microfluidic mRNA Display |
|---|
| R33 |
ZENG, YONG (contact); GODWIN, ANDREW K; SAMUEL, GLENSON |
Integrated exosomes profiling for minimally invasive diagnosis and monitoring of cancer |
|---|
| R33 |
BROWN, BRIAN D |
Pro-Codes: A novel vector and cell barcoding technology |
|---|
| R33 |
SCHRUM, ADAM G |
Multiplex matrix ELISA for T cell protein-interaction networks in cancer |
|---|
| R21 |
ROYZEN, MAKSIM |
Development of Catch and Release Approach for Multi-Drug Local Delivery of Chemotherapies |
|---|
| R21 |
GULLEY, MARGARET L |
EndoGenus Toolkit: A Biometric Method for Absolute Quantification of Tumor Markers by Massive Parallel Sequencing |
|---|
| R21 |
FU, XIAO-AN |
A microreactor chip platform for quantitative analysis of unsaturated aldehydes in exhaled breath |
|---|
| R33 |
BORGES, CHAD R |
Validation and Advanced Development of Albumin Oxidizability as a Marker of Plasma/Serum Integrity |
|---|
| R21 |
SHI, TUJIN |
An ultrasensitive targeted mass spectrometry system for proteomics analysis of single cells |
|---|
| R21 |
VAN DEVENTER, JAMES ALLEN |
Discovering hybrid inhibitors for tumor microenvironment disruption |
|---|
| R21 |
ENGLER, ADAM JEFFREY |
Developing Adhesome Technology as a Physical Marker of Highly Metastatic Cells |
|---|
| R33 |
LIU, YANG |
High-throughput super-resolution imaging of chromatin structures at different epigenetic states |
|---|
| R33 |
LU, JUN |
CRISPR-based Enhanced Molecular Chipper Technology for Identifying Functional Noncoding Elements in Cancer |
|---|
| R21 |
KARGINOV, ANDREI V (contact); REHMAN, JALEES |
Optogenetic tools for the dissection of oncogenic signaling mediated by kinases |
|---|
| R21 |
SMITH, LLOYD M |
Novel NeuCode Tagging Reagents for Identification and Quantification of Intact Proteoforms in Cancer Tissues |
|---|
| R33 |
INCE, TAN A |
Live Tumor Culture Core and Tissue Specific Culture (TSC) System for Human Cancers |
|---|
| R33 |
SALIPANTE, STEPHEN J |
Advanced development and validation of genome-scale molecular diagnostics for microsatelliteinstability using targeted molecular counting methods |
|---|
| R21 |
FIELDS, RYAN C |
Advancing Cancer Biology, Diagnostics and Therapeutics Outside of the Patient: Creation of a Novel, Autologous, Ex Vivo, Vascularized Model of the Tumor Microenvironment |
|---|
| R21 |
ROBLES, FRANCISCO E |
Stimulated Raman scattering spectroscopic optical coherence tomography (SRS-SOCT) for label-free molecular imaging of brain tumor pathology |
|---|
| R21 |
BRENT, ROGER |
Precision controllers of mammalian gene expression |
|---|
| R33 |
CIMA, MICHAEL J |
Advanced development and validation of microdevices for high-throughput in situ drug sensitivity testing in tumors |
|---|
| R21 |
VAN DAM, ROBERT MICHAEL |
High-throughput radiochemistry platform for accelerated discovery and development of novel PET imaging agents for cancer |
|---|
| R33 |
CHENG, JI-XIN |
Quantitative SRS Imaging of Cancer Metabolism at Single Cell Level |
|---|
| R21 |
MOHS, AARON M |
Tunable Fluorescent Organic Nanoparticles for Cancer Imaging Applications |
|---|
| R33 |
WALTER, MATTHEW J (contact); DUNCAVAGE, ERIC J |
TARGETED SINGLE-MOLECULE SEQUENCING ASSAY INCORPORATING MOLECULAR BARCODES |
|---|
| R33 |
PARKER, LAURIE L |
Fluorescence lifetime-based single fluorophore biosensors of post-translational modification enzyme activity |
|---|
| R33 |
PATTENDEN, SAMANTHA GAIL (contact); DAVIS, IAN J; DAYTON, PAUL A |
The application of Enhanced Cavitation to enable DNA and Chromatin Extraction from Archived Tissues |
|---|
| R21 |
KRON, STEPHEN J |
Tag-ChIP-MS for analysis of chromatin-level regulation of DNA repair |
|---|
| R33 |
LEVENSON, RICHARD M |
Cancer histology and QC via MUSE: Sample-sparing UV surface-excitation microscopy |
|---|
| R21 |
ABBOTT, KAREN L. |
Novel Platform linking cancer-specific glycosylation with cell signaling outcomes |
|---|
| R21 |
MAILLOUX, ADAM WILLIAM |
Autohistomagnetic Isolation of Tumor-reactive T-cells |
|---|
| R21 |
SCHIBEL, ANNA |
Microsatellite Sequencing to Enable Cancer Genotyping |
|---|
| R33 |
LEVINSON, NICHOLAS MARK |
Time-resolved FRET-based allostery sensors for any protein kinase drug target |
|---|
| R33 |
HIGGINSON, DANIEL |
Comprehensive breakpoint analyses for simultaneous quantification of all DNA double strand break repair pathways |
|---|
| R33 |
HALL, ADAM ROGER |
Detecting diverse nucleic acid biomarkers of cancer with solid-state nanopores |
|---|
| R33 |
WANG, SIYUAN (contact); MUZUMDAR, MANDAR DEEPAK |
Multiplexed imaging of chromatin folding and RNA profiles in cancer |
|---|
| R21 |
GUPTA, GAUTAM |
Bio CaRGOS: Capture and release gels for optimized storage of Cancer Biospecimens |
|---|
| R21 |
LIANG, FU-SEN |
Spatiotemporal Epitranscriptome Editing Technology |
|---|
| R33 |
BHATNAGAR, PARIJAT |
T-cell Biofactories for targeting extracellular matrix |
|---|
| R21 |
LI, WEI |
Fractionation and Profiling of Heterogeneous Circulating Tumor Cells Using a Hyperuniform- Structured Microchip |
|---|
| R33 |
RECHT, MICHAEL |
High-Throughput Screening Platform for Cancer Drug Discovery |
|---|
| R33 |
HASHAM, MUNEER GULAMHUSEIN |
Impact of Genetic Diversity on Human Xenograft Tumor Growth |
|---|
| R21 |
TEWARI, MUNEESH (contact); JOHNSON-BUCK, ALEXANDER EDMUND; WALTER, NILS G |
Highly specific, amplification-free, single-molecule counting of rare methylated DNA cancer biomarkers |
|---|
| R33 |
Wang, Shaopeng |
A Virion-Display Oscillator Array and Detection Platform for Quantification of Transmembrane Protein Binding Kinetics |
|---|
| R21 |
SEELIG, GEORG (contact); WU, DAVID |
High-resolution spatial transcriptomics through light patterning |
|---|
| R33 |
CHEN, FEI (contact); REGEV, AVIV ; RODIG, SCOTT J |
Clinical implementations of spatial transcriptomics in tumors |
|---|
| R33 |
FAN, RONG (contact); LU, JUN |
High-throughput single-cell co-sequencing of small and large RNAs to identify molecular circuitry in cancer |
|---|
| R21 |
CICERONE, MARCUS T |
Label-Free Cell-Resolved Metabolomics for Tumor Microscopy |
|---|
| R21 |
HUR, SOOJUNG CLAIRE |
Development of a microfluidic primary cell editing platform (pCEP) for personal gene therapy |
|---|
| R33 |
WEI, CHIA-LIN (contact); VERHAAK, ROEL GW |
Advancing Ultra Long-read Sequencing and Chromatin Interaction Analyses for Chromosomal and Extrachromosomal Structural Variation Characterization in Cancer |
|---|
| R21 |
MANALIS, SCOTT R |
Building microenvironment-containing organoids from patient samples with single-cell precision |
|---|
| R33 |
DE VLAMINCK, IWIJN (contact); BRITO, ILANA LAUREN; ZIPFEL, WARREN R |
Spatially Resolved Metagenomics to Explore Tumor-Microbiome Interactions in Human Colorectal Cancer |
|---|
| R33 |
SOPER, STEVEN ALLAN (contact); AUGUST, KEITH |
Increased Sensitivity of Minimal Residual Disease Monitoring using Peripheral Blood in Pediatric Patients with Acute Lymphoblastic Leukemia |
|---|
| R21 |
KEUNG, ALBERT |
Intracellular CRISPR gRNA assembly for massively multiplexed, one pot, (epi)genetic screening |
|---|
| R21 |
O'NEILL, RACHEL |
Development and Utilization of Splice-specific Antibodies |
|---|
| R21 |
MONTAGNA, CRISTINA (contact); LENZ, JACK R |
Development of a high-resolution mapping platform for HPV DNA integration in premalignant lesions |
|---|
| R21 |
IM, HYUNGSOON |
Nano-plasmonic technology for high-throughput single exosome analyses |
|---|
| R33 |
SCHIAVINATO EBERLIN, LIVIA |
Advanced Development of the MasSpec Pen for Cancer Diagnosis and Surgical Margin Evaluation |
|---|
| R33 |
VAN DAM, ROBERT MICHAEL |
Optimization and validation of integrated microscale technologies for low-cost, automated production of PET molecular imaging tracers for cancer research |
|---|
| R21 |
ANDRES-MARTIN, LAURA |
Establishing efficient technologies for ovarian cancer organoid derivation from fresh tumor resections |
|---|
| R21 |
ALEXANDRAKIS, GEORGIOS |
Nanotechnology Enabled Selection of MHC-Peptide Ligands to Personalize Cancer Therapy |
|---|
| R21 |
HATTORI, TAKAMITSU |
Rational generation of high-performance recombinant antibodies to post-translational modifications |
|---|
| R33 |
KETTENBACH, ARMINJA NADINE (contact); GERBER, SCOTT A |
Activity based profiling of Phosphoprotein phosphatases in cancer using mass spectrometry-based proteomics |
|---|
| R33 |
YANG, JENNY J |
Multi-color Mapping of Cancer Molecular Signatures and Tumor microenvironment |
|---|
| R33 |
TAVANA, HOSSEIN (contact); LUKER, GARY D |
A High Throughput Human Tumor Modeling Technology for Cancer Drug Discovery |
|---|
| R21 |
KENTSIS, ALEX |
Multi-dimensional targeted mass spectrometry technology for pathway-scale functional proteomics |
|---|
| R33 |
SCHNECK, JONATHAN P |
A high-throughput nanoparticle assay to characterize cancer neoepitope-specific T cells |
|---|
| R21 |
WARREN, CHRISTOPHER L (contact); OZERS, MARY SZATKOWSKI |
SNAP-X: Development of a Mutagenesis Strategy and High Density Protein Array to Comprehensively Display Protein Variants |
|---|
| R21 |
SINGAMANENI, SRIKANTH (contact); MORRISSEY, JEREMIAH J |
METAL-ORGANIC FRAMEWORK AS PROTECTIVE COATING FOR CANCER BIOSPECIMEN PRESERVATION |
|---|
| R21 |
KIM, HYUN JUNG |
A personalized colorectal cancer-on-a-chip for assessing tumor-microbiome crosstalk |
|---|
| R21 |
MARTO, JARROD A (contact); BUHRLAGE, SARA J |
Tools for DUB Drug Discovery |
|---|
| R33 |
JIANG, NING |
An integrated therapeutic T cell receptor screening platform for adoptive cell therapy in cancer |
|---|
| R21 |
ZHU, YAZHEN (contact); AGOPIAN, VATCHE ; TSENG, HSIAN-RONG |
Click Chemistry-Mediated Microfluidic Sorting for HCC CTCs |
|---|
| R33 |
CHEN, SIDI |
Rapidly scalable platforms for direct in vivo screening of functional drivers in lethal cancers |
|---|
| R21 |
WEISSLEDER, RALPH |
Single Circulating Vesicle Analysis for Early Cancer Detection |
|---|
| R21 |
GARBER, MANUEL |
A modular, customizable sequencing system for simultaneous genotyping and transcript analysis in single cells |
|---|
| R21 |
BHATNAGAR, PARIJAT |
T-cell Biofactories for targeting interstitial fluid pressure |
|---|
| R33 |
BREUNIG, JOSHUA JOHN |
GESTALT Barcoding and Single-cell Transcriptomics of Tumor Cell Evolution in Personalized Tumor Models |
|---|
| R21 |
SEIBEL, ERIC J |
Rapid Needle Biopsy Assessment at Point of Care to advance personalized cancer therapy |
|---|
| R33 |
COOKS, ROBERT GRAHAM (contact); CHAICHANA, KAISORN LEE; QUINONES-HINOJOSA, ALFREDO |
Advanced Development of Desorption Electrospray Ionization Mass Spectrometry for Intraoperative Molecular Diagnosis of Brain Cancer using Pathology Biopsies |
|---|
| R21 |
WU, YUN (contact); GAN, QIAOQIANG |
Exosome-Protein-microRNA-OneStop (Exo-PROS) biosensor: a new liquid biopsy for cancer screening and early detection |
|---|
| R33 |
LEI, YUGUO |
A Single Conical Tube Device for Precision CAR-T Cells Manufacturing |
|---|
| R33 |
FIOLKA, RETO PAUL |
Multiscale microscope for 3D cancer imaging in model organisms and organoids |
|---|
| R21 |
YAMAMOTO, KEITH ROBERT (contact); KROGAN, NEVAN J |
CasCUT&RUN: An in vivo method to analyze locus-specific protein complexes driving transcription of target genes in cancer |
|---|
| R21 |
REVZIN, ALEXANDER |
A microfluidic cell culture platform for personalizing pancreatic cancer therapies |
|---|
| R21 |
ANGEL, PEGGY M |
Enzymatic Tools for 2D Tissue Localized and Deeper Proteomic Sequencing of Cancer Stromal Proteins |
|---|
| R21 |
HUANG, XIAOHUA |
Technology for measuring telomere length of individual chromosomes of single cancer cells |
|---|
| R21 |
SKARDAL, ALEKSANDER (contact); STROWD, ROY ERVIN |
Predicting Tumor Heterogeneity Evolution After Therapy In Patient-Derived Ex Vivo Glioblastoma Organoids |
|---|
| R21 |
SHVETS, GENNADY |
Phenotypic assay for drug discovery and personalized medicine based on real-time vibrational spectroscopy enhanced by plasmonic metasurfaces |
|---|
| R21 |
FOLCH, ALBERT |
High-content functional cancer drug testing on micro-cuboidal tumor dissections |
|---|
| R33 |
SPICER, TIMOTHY PATRICK |
Advanced Development and Validation of 3 Dimensional Spheroid Culture of Primary Cancer Cells using Nano3D Technology |
|---|
| R33 |
WEISS, GREGORY A |
Monitoring Recurrent Bladder Cancer with Electro-Phage Biosensors |
|---|
| R21 |
GAMCSIK, MICHAEL |
High-Throughput Screening Under Static or Dynamic Hypoxia |
|---|
| R33 |
LIN, QIAO |
Validating Rapid Microfluidic Isolation of Personalized Aptamers for Monitoring Minimal Residual Disease in Multiple Myeloma |
|---|
| R33 |
WU, YUN |
Noninvasive detection of circulating RNAs for lung cancer early detection and prognosis |
|---|
