R33CA240201 |
VAN DAM, ROBERT MICHAEL |
Optimization and validation of integrated microscale technologies for low-cost, automated production of PET molecular imaging tracers for cancer research |
R21CA217662 |
IM, HYUNGSOON |
Nano-plasmonic technology for high-throughput single exosome analyses |
R21CA246358 |
SEELIG, GEORG (contact); WU, DAVID |
High-resolution spatial transcriptomics through light patterning |
R33CA246363 |
LEVINSON, NICHOLAS MARK |
Time-resolved FRET-based allostery sensors for any protein kinase drug target |
R21CA223727 |
HUANG, XIAOHUA |
Technology for measuring telomere length of individual chromosomes of single cancer cells |
R21CA247638 |
LIANG, FU-SEN |
Spatiotemporal Epitranscriptome Editing Technology |
R33CA247739 |
BHATNAGAR, PARIJAT |
T-cell Biofactories for targeting extracellular matrix |
R33CA225458 |
KETTENBACH, ARMINJA NADINE (contact); GERBER, SCOTT A |
Activity based profiling of Phosphoprotein phosphatases in cancer using mass spectrometry-based proteomics |
R21CA240185 |
LI, WEI |
Fractionation and Profiling of Heterogeneous Circulating Tumor Cells Using a Hyperuniform- Structured Microchip |
R21CA251952 |
FOLCH, ALBERT (contact); PIERCE, ROBERT H |
High-content functional cancer drug testing on micro-cuboidal tumor dissections |
R33CA246448 |
HALL, ADAM ROGER |
Detecting diverse nucleic acid biomarkers of cancer with solid-state nanopores |
R33CA225539 |
JIANG, NING JENNY |
An integrated therapeutic T cell receptor screening platform for adoptive cell therapy in cancer |
R21CA256084 |
DI CARLO, DINO |
Lab on a particle technology for functional screening of therapeutic cells |
R21CA256128 |
DEININGER, MICHAEL W |
A Bioluminescent Assay for Direct Measurement of Sirtuin Activity in Cancer Cells |
R21CA240199 |
O'NEILL, RACHEL |
Development and Utilization of Splice-specific Antibodies |
R33CA235597 |
SOPER, STEVEN ALLAN (contact); AUGUST, KEITH |
Increased Sensitivity of Minimal Residual Disease Monitoring using Peripheral Blood in Pediatric Patients with Acute Lymphoblastic Leukemia |
R21CA258008 |
SCARCELLI, GIULIANO (contact); KONSTANTOPOULOS, KONSTANTINOS ; MARTIN, STUART S |
Stimulated Brillouin Flow Cytometry for biomechanical assessment of metastatic potential |
R21CA229024 |
HUR, SOOJUNG CLAIRE |
Development of a microfluidic primary cell editing platform (pCEP) for personal gene therapy |
R21CA247647 |
WILSON, GERALD M |
Suppressing oncogenic RNA regulons using engineered zinc finger ribonucleases |
R21CA256082 |
BAR-PELED, LIRON |
Chemical Proteomic Identification of Druggable Oncogenic Transcription Factors |
R21CA257980 |
BELCHER, ANGELA M (contact); MALEY, CARLO |
A cell-cycle induced genetic recorder for simultaneous recovery of cell divisions and lineage |
R33CA247700 |
JI, HANLEE P |
Multimodal iterative sequencing of cancer genomes and single tumor cells |
R21CA236653 |
ISSADORE, DAVID AARON |
High Throughput Digital Droplet ELISA for Ultrasensitive Multiplexed Diagnostics |
R33CA235294 |
WANG, SHAOPENG |
A Virion-Display Oscillator Array and Detection Platform for Quantification of Transmembrane Protein Binding Kinetics |
R21CA250597 |
ZHANG, FANGLIANG |
Targeted degradation of proteins by affinity peptide conjugated ubiquitin (APCU) |
R21CA251015 |
STILL, AMANDA NICOLE HAYMOND |
New Hybrid Molecular Modalities Comprised of DNA-Origami and Interfering Peptides as Inhibitors of Protein-Protein Interactions |
R21CA255894 |
XIAO, HAN (contact); YUSTEIN, JASON |
Development of Bone-Targeting Antibodies for Ewing Sarcoma Using Genetic Code Expansion |
R21CA256081 |
SWAGER, TIMOTHY M |
Innovative Droplet Lenses for NextGen Light Sensors of Biomarkers of Inflammation |
R33CA255893 |
SEELIG, GEORG |
Joint receptor and protein expression immunophenotyping through split-pool barcoding |
R33CA257878 |
HANSEN, ANDERS SEJR |
Super-resolution microscopy for dynamic analysis of focal enhancer amplifications in cancer |
R21CA236665 |
SANTORE, MARIA M |
Paper-based Breastmilk Collection System for Facile, In-Home Use |
R21CA258019 |
CHEN, KAI (contact); MCKENNA, CHARLES E |
Novel Bisphosphonate PET Probes for Myeloma Bone Disease |
R33CA247744 |
GARTNER, ZEV JORDAN |
Universal Sample Multiplexing for Single Cell Analysis |
R33CA251006 |
HAUN, JERED BRACKSTON |
Microfluidic tumor tissue processing platform for single cell diagnostics |
R33CA258016 |
LIU, XUEFENG |
Validating Urine Derived Cancer Cells (UDCC) -- Non-Invasive and Living Liquid Biopsies -- in Bladder Cancer Clinics |
R33CA252158 |
ZENG, YONG (contact); XU, LIANG |
Integrative Functional Profiling of Tumor-Derived Extracellular Vesicles |
R21CA251027 |
SCHULMAN, REBECCA |
Secretion responsive Hydrogels for Identification of Functional single T cells (SHIFT) |
R21CA251043 |
HOSHIKA, SHUICHI |
High Quality Proteins with Multiple Post Translational Modifications |
R21CA255979 |
DIDENKO, VLADIMIR V |
In situ assay imaging nuclear RNA exosome activity for cancer studies |
R21CA261734 |
AKSAN, ALPTEKIN |
Novel cryopreservation method for stabilization of manufactured therapeutic cells |
R21CA261737 |
HAINER, SARAH JANE (contact); SHI, YI |
Using nanobodies to increase the sensitivity and resolution of chromatin profiling through uliCUT&RUN |
R21CA263147 |
BHARGAVA, ROHIT |
Spectroscopy Assisted Laser Microdissection |
R21CA272345 |
KNOWLES, DAVID ARTHUR |
A CRISPR/Cas13 approach for identifying individual transcript isoform function in cancer |
R33CA256086 |
JIANG, NING JENNY (contact); BROCK, AMY |
A streamlined, high-throughput platform for validation of cancer antigen presentation and isolation of cancer antigen reactive T cells |
R33CA256112 |
WEI, WEI |
Liquid biopsy-based toolkits for neoantigen and cognate TCR discovery for cancer immunotherapy |
R33CA261726 |
CHENG, JI-XIN |
Mapping Cancer Metabolism by Mid-infrared Photothermal Microscopy |
R21CA250999 |
BORGES, CHAD R |
Aliquot-level visual indicators of biospecimen exposure to thawed conditions |
R21CA257864 |
BOYLE, ALAN P |
High-throughput inverted reporter assay for characterization of silencers and enhancer blockers |
R21CA267222 |
LEE, HAKHO |
3D Fourier Imaging System for High Throughput Analyses of Cancer Organoids |
R21CA267260 |
ARMITAGE, BRUCE A (contact); ZHANG, HUAIYING |
Fluorescent gammaPNA Miniprobes for Imaging Telomeric RNA |
R33CA267226 |
DRAKE, RICHARD R |
Targeted Isolation and Identification of Sialylated Glycoproteins in Cancer Tissues, Cells and Biofluids |
R21CA267012 |
SNYDER, JOSHUA CLAIR |
Mouse Paint: A massively combinatorial approach for illuminating tumor heterogeneity in True Color |
R21CA269103 |
BLAINEY, PAUL CLARK |
Stitch-seq for genome-wide pooled genomic screening with RNA-seq readout |
R33CA267221 |
NORMAN, THOMAS MAXWELL (contact); LOWE, SCOTT W |
Systematic characterization of cancer variants using single-cell functional genomics |
R33CA269015 |
ADEY, ANDREW |
Accessible high-throughput single-cell genome sequencing |
R21CA261775 |
LIN, QIAO |
A Practical Approach to Tumor-Specific Aptamers for B-Cell Hematologic Malignancies |
R33CA258012 |
KARGINOV, ANDREI V (contact); REHMAN, JALEES |
Optogenetic Control of Tumor Initiation and Tumor Progression in vivo |
R33CA269094 |
MOELLERING, RAYMOND E |
Single-Cell Protein Activity Profiling in Breast Cancer Cells and Tissues |
R21CA267245 |
SHIBATA, DARRYL K |
Photolithographic Tumor DNA Isolation |
R21CA269091 |
BORGES, CHAD R |
Plate reader assays to forensically assess exposure of plasma and serum to thawed conditions |
R33CA261696 |
MERAJVER, SOFIA DIANA (contact); OLIVER, CHRISTOPHER RYAN |
Advanced development and validation of an in vitro platform to phenotype brain metastatic tumor cells using artificial intelligence |
R33CA269100 |
CHIU, BRIAN C-H (contact); ZHANG, WEI |
A highly sensitive linear amplification based DNA methylation profiling technique for clinical cancer research |
R21CA269099 |
YAKOVLEV, VLADISLAV V (contact); BEREZIN, MIKHAIL Y |
Molecular and cellular imaging of bone biopsies using AI augmented deep UV Raman microscopy |
R21CA272014 |
SALIPANTE, STEPHEN J |
Efficient, cost-effective, and ultrasensitive sequencing of somatic mutations |
R33CA259451 |
NAEGLE, KRISTEN M |
A synthetic toolkit for the recombinant production of tyrosine phosphorylated proteins and peptides |
R21CA257816 |
COUNTER, CHRISTOPHER M (contact); ABBRUZZESE, JAMES L |
Adapting K-MDS to detect KRAS-mutant ctDNA |
R21CA257942 |
GIBBS, SUMMER LYNNE |
A Novel Fluorescence Imaging Platform to Predict Response to Combinatorial Tyrosine Kinase Inhibitors |
R21CA261642 |
NABA, ALEXANDRA (contact); GAO, YU |
Enhanced mass-spectrometry-based approaches for in-depth profiling of the cancer extracellular matrix |
R21CA261643 |
TANG, SINDY KAM-YAN |
A micro-dissection platform for generating uniform-sized patient-derived tumor organoids (PDOs) for personalized cancer therapy |
R21CA272326 |
KELLY, RYAN T |
In-depth and label-free proteome profiling of hundreds of single cells per day |
R21CA272351 |
SOPER, STEVEN ALLAN |
Molecular Sub-typing Breast Cancer Patients using a Liquid Biopsy |
R33CA267219 |
LANDAU, DAN |
Expanding the GoT toolkit to link single-cell clonal genotypes with protein, transcriptomic, epigenomic and spatial phenotypes |
R33CA267258 |
LEE, ABRAHAM P (contact); AGRAWAL, ANSHU |
Microfluidic Precision Engineered Artificial Antigen Presenting Cells for Cancer Immunotherapy |
R33CA272321 |
WANG, TZA-HUEI JEFF (contact); PISANIC II, THOMAS RUSSELL |
A low-cost, multiplexed digital high resolution melt platform for DNA methylation-based detection and identification of cancers in liquid biopsies |
R33CA272357 |
PAN, TAO (contact); BISSONNETTE, BRUCE MARC; SHOGAN, BENJAMIN |
Transfer RNA sequencing and application to cancer research and clinics |
R33CA277820 |
WEISSLEDER MD PHD, RALPH |
Bioorthogonal probe development for highly parallel in vivo imaging |
R33CA278392 |
KLEIN, ALLON MOSHE (contact); MAZUTIS, LINAS |
Micro-capsules for versatile multiplexed cytometry |
R61CA278445 |
DHAKAL, SOMA |
Single-Molecule High-Confidence Detection of miRNA Cancer Biomarkers |
R61CA278531 |
SHIRURE, VENKTESH |
Microfluidic technology to isolate tumoricidal T-cells from peripheral blood |
R33CA278393 |
VAN GALEN, PETER (contact); SANKARAN, VIJAY GANESH |
Clonal analysis of cancer by mitochondrial DNA barcoding |
R33CA278510 |
DUNCAVAGE, ERIC J (contact); SPENCER, DAVID H |
A Rapid and Comprehensive Approach for Clinical Genomic Profiling in Lung Cancer |
R61CA278558 |
YAN, HAO (contact); HARIADI, RIZAL FAJAR |
High-throughput, purification-free, and ultrasensitive transmembrane nanosensor arrays for digital counting of microRNA biomarkers of intact exosomes |
R33CA278469 |
JI, HANLEE P |
Single cell modeling of cancer mutations |
R33CA278544 |
LEVENSON, RICHARD M |
CoreView and FIBI for rapid-onsite evaluation and molecular profiling of core-needle breast biopsies. |
R33CA278551 |
ISSADORE, DAVID AARON (contact); CARPENTER, ERICA |
Combining Machine Learning and Nanofluidic Technology for The Multiplexed Diagnosis of Pancreatic Adenocarcinoma |
R61CA278398 |
GAO, XIAOJING J (contact); WINSLOW, MONTE MEIER |
Program the Immune System against RAS-driven Cancer |
R61CA278459 |
PRATX, GUILLEM |
A Novel Assay to Individualize Resensitization of Iodine-Refractory Thyroid Cancer |
R61CA278559 |
LU, YUE |
Vesicle Epitope Transcript sequencing (VET-seq): Droplet-based Multiomic Profiling Platform for Single Vesicle Analysis |
R33CA272271 |
CUNNINGHAM, BRIAN T (contact); MANSFIELD, AARON SCOTT; WANG, XING |
Rapid, simple, and ultrasensitive quantitation of KRAS ctDNA at the point of care using CRISPR/Cas amplification and digital resolution biosensor microscopy |
R33CA272331 |
MURETTA, JOSEPH M (contact); GORDON, WENDY RYAN |
Engineering Protein Modulators of Notch Activation for T-cell immunotherapy |
R33CA281702 |
CHEN, SIDI |
Advanced development of composite gene delivery and CAR engineering systems |
R33CA281802 |
LABAER, JOSHUA |
Multiplex In-Solution Protein Array (MISPA) for high throughput, quantitative, early profiling of pathogen-induced head and neck |
R33CA281875 |
BRUDNO, YEVGENY |
MASTER Scaffolds for Rapid, Single-Step Manufacture and Prototyping of CAR-T cells |
R33CA281918 |
YE, LI (contact); CRAVATT, BENJAMIN F |
A platform to identify in vivo targets of covalent cancer drugs in 3D tissues |
R61CA278402 |
BRAVO CORDERO, JOSE JAVIER |
Intersectional genetics-based biosensors for dormant cancer cells |
R61CA281657 |
LUKER, GARY D |
Integrated Imaging Tools for Intercellular Chemokine Signalling |
R61CA281667 |
FERNANDEZ, FACUNDO MARTIN |
Triboelectric Ambient Mass Spectrometry Imaging of Renal Cell Carcinomas |
R61CA281807 |
HACOHEN, NIR |
Development of methods for highly multiplexed quantification of cancer proteomes using large-scale nanobody libraries |
R61CA278452 |
SHAH, NEEL H |
A Generalizable Photo-Crosslinking Strategy to Identify Tyrosine Phosphatase Substrates |
R61CA281795 |
CAMPAGNOLA, PAUL J (contact); YESILKOY, FILIZ |
A novel multimodal ECM analysis platform for tumor characterization combining morphological and spectrochemical tissue imaging approaches. |
R33CA281602 |
MEYER, KATHRYN D |
A High-Throughput Screening Platform to Discover RNA Methylation Inhibitors |
R21CA251052 |
SHVETS, GENNADY |
Phenotypic assay for drug discovery and personalized medicine based on real-time vibrational spectroscopy enhanced by plasmonic metasurfaces |