Annual PI Meeting for the Innovative Molecular Analysis Technologies (IMAT) Program (Agenda)

Agenda

The meeting will be at the NCI Shady Grove campus at 9609 Medical Center Drive, Rockville MD 20850.
All sessions are in the lower terrace level of the building.

Pre-meeting Sunday, November 8, 2026
5:00pm Happy Hour at Kareem's Lebanese Kitchen at Rio Lakefront in Gaithersburg

Day 1: Monday, November 9, 2026

10:00am	Opening Comments (TE 406/408/410) Kelly Crotty, NCI Center for Strategic Scientific Initiatives Satish Gopal, NCI Acting Deputy Director for Scientific Strategy and Development, Director of Center for Global Health
10:10am	Session 1: Cancer Model Systems Enabling in vivo barcoded single-cell multiomics-compatible genome-wide screens in personalized tumor models using defined-copy somatic transgenesis Joshua Breunig, Wake Forest University School of Medicine Development and validation of demineralized bone paper-based human bone remodeling assays Jungwoo Lee, University of Massachusetts Amherst Microphysiological platform for analyzing multiple myelomas tumor microenvironment, enabling immunotherapy assessment and drug screening Tania Konry, Northeastern University
11:10am	Break
11:25am	Session 2: Proteomics Methods AI-controlled autonomous proteomics for deep, high-throughput clinical proteome profiling Wilhelm Haas, Massachusetts General Hospital, Harvard Medical School, and Broad Institute 3D proteomics at single cell resolution with covalent protein painting Casimir Bamberger, The Scripps Research Institute
12:05pm	Panel Discussion: Integrating Machine Learning with Experimental Technologies Moderators: Subhashini Jagu, NCI Office of Data Sharing and Asif Rizwan, NCI Division of Cancer Treatment and Diagnosis Panelists: Wilhelm Haas, Massachusetts General Hospital, Harvard Medical School, and Broad Institute K. Chris Garcia, Stanford University Daniel Bergman, University of Maryland Georg Seelig, University of Washington
12:45pm	Lunch
1:45pm	Session 3: Liquid Biopsy Technologies Nano-CRIPSR extracellular vesicle sensing system for longitudinal tumor monitoring Hyungsoon Im, Massachusetts General Hospital Rapid ultra sensitive assays and detection instrument for digital resolution detection of molecular biomarkers in point-of-care environments Xing Wang, University of Illinois at Urbana-Champaign Vesicle Epitope Transcript sequencing (VET-seq): Droplet-based multiomic profiling platform for single vesicle analysis Christopher Lausted, Institute for Systems Biology High throughput digital droplet assays for ultrasensitive multimodal (DNA, RNA, and protein) diagnostics David Issadore, University of Pennsylvania
3:05pm	Trainee FlashTalks Laser Microbiopsy Allows for Precision Ultra Small Skin Tissue Harvest Andrew Ferrer, University of Texas at Austin An On-Demand Stiffening 3D Bone Marrow Platform to Model Disease-Associated Niche Remodeling Kexin Zhang, University of Pennsylvania Optimization of an approach to enrich translationally active bacteria from saliva for characterization of microbial contributors to oral squamous cell carcinoma Nicole Nightingale, University of Minnesota Genetically encoded vibrational proteins for functional imaging of biomolecular assemblies in living cells Yuwei Sun, Boston University Advancing Spray-Capillary CE-MS for Ultrasensitive and Deep Top-Down Proteomics of Mass-Limited Samples Kellye Cupp-Sutton, University of Alabama Rare Cell Hunting: Mapping Genotype to Phenotype of Rare Mutant Cells in Clonal Hematopoiesis with Genotyping of Targeted Hotspots and mRNA (GoTHam) Joe Pelt, Weill Cornell
3:40pm	Poster Session (Seminar 110)
	3:40 - Odd Numbered Posters
	4:40 - Even Numbered Posters
5:40pm	Adjourn

6:45pm: Group Dinner at Kareem's Lebanese Kitchen at Rio Lakefront in Gaithersburg
All attendees welcome - please RSVP

Day 2: Tuesday, November 10, 2026

9:00am	Opening Comments (TE 406/408/410) Kelly Crotty, NCI Center for Strategic Scientific Initiatives
9:15am	Session 4: Spatial-omics Methods Spatially resolved multi-omics sequencing of FFPE tissues at cellular level Yanxiang Deng, University of Pennsylvania High-dimensional spatial interactomics of cancer signaling networks and signalosomes by intelligent sequential proximity ligation assays Ahmet Coskun, Georgia Institute of Technology Spatial genomics to decode cancer evolution in tissues Fei Chen, Broad Institute
10:15am	Social Networking with NCI Program Staff
11:15am	Session 5: Immunoengineering Approaches Hydrogel-mediated in situ programming of T-cell memory for enhanced antitumor immunity Jonathan Schneck, Johns Hopkins School of Medicine Targeted cancer ablation via programmable sensing of amplified oncogenic RNA Meng Zhang, Stanford University Next-generation platforms for interrogating TCR specificity K. Christopher Garcia, Stanford University
12:15pm	Lunch Concurrent: Early Career Session (Seminar 110) Michael Schmidt, NCI Center for Cancer Training Jessica Calzola, NCI Center to Reduce Cancer Health Disparities NCI fellowships and career development funding opportunities
1:15pm	Commercialization and Value Proposition Workshop John Sullivan, NIH Entrepreneur-in-Residence
2:15pm	Panel Discussion: Pathways for Technology Dissemination Moderator: Jonathan Franca-Koh, NCI Small Business Innovation Research (SBIR) Center Panelists: John Sullivan, NIH Entrepreneur-in-Residence Shane Peng, AstraZeneca, Academic Partnerships Jonathan Schneck, Johns Hopkins School of Medicine David Issadore, University of Pennsylvania
3:00pm	Break
3:15pm	Session 6: High Throughput Assays to Interrogate Cell State In search of treatment for glioblastoma: Developing a multiplexed high throughput screen targeting cellular membrane voltage and cell cycle state Matthew Shorey, Houston Methodist CROPseq-multi: A universal solution for multiplexed perturbation in high-content pooled CRISPR screens Russell Walton, Broad Institute
3:55pm	Session 7: Detecting and Engineering Molecular Interactions Quantification of molecular interactions across the matrix spectrum enables cancer research Amanda Kussrow, Vanderbilt University Evolved molecules that destroy cancer relevant proteins Elisa Biondi, Foundation for Applied Molecular Evolution CRISPRa-mediated transcriptional detection and cellular reprogramming identified regulators of tumor-derived IFN-I Jeffrey Ishizuka, Yale School of Medicine New chemical tools for covalent drug discovery Jarrod Marto, University of Virginia
5:15pm	Closing Comments