Childhood Cancer Data Initiative Annual Symposium (Abstract Registration): Submission #34

serial: '34'
sid: '147985'
uuid: 5d3174b0-7f9a-4ec8-8d76-9dc04b0a829f
uri: /nci/ccdisymposium/abstract
created: '1754331174'
completed: '1754331280'
changed: '1754331280'
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langcode: en
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entity_id: '2139'
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data:
  authors_:
    - add_author_degree: ''
      add_author_first_name: Joshua
      add_author_last_name: Shapiro
      add_author_middle: A
      add_author_organization: "Alex's Lemonade Stand Foundation"
    - add_author_degree: ''
      add_author_first_name: Stephanie
      add_author_last_name: Spielman
      add_author_middle: J
      add_author_organization: "Alex's Lemonade Stand Foundation"
    - add_author_degree: ''
      add_author_first_name: Allegra
      add_author_last_name: Hawkins
      add_author_middle: G
      add_author_organization: "Alex's Lemonade Stand Foundation"
    - add_author_degree: ''
      add_author_first_name: Deepashree
      add_author_last_name: 'Venkatesh Prasad'
      add_author_middle: ''
      add_author_organization: "Alex's Lemonade Stand Foundation"
    - add_author_degree: ''
      add_author_first_name: Jennifer
      add_author_last_name: "O'Malley"
      add_author_middle: ''
      add_author_organization: "Alex's Lemonade Stand Foundation"
    - add_author_degree: ''
      add_author_first_name: David
      add_author_last_name: Mejia
      add_author_middle: S
      add_author_organization: "Alex's Lemonade Stand Foundation"
    - add_author_degree: ''
      add_author_first_name: Jaclyn
      add_author_last_name: Taroni
      add_author_middle: 'N'
      add_author_organization: "Alex's Lemonade Stand Foundation"
  abstract: |-
    The Open Single-cell Pediatric Cancer Atlas (OpenScPCA) project is an open, collaborative initiative to analyze publicly available data from the Single-cell Pediatric Cancer Atlas (ScPCA) Portal. The goal of OpenScPCA is to enhance the utility of single-cell pediatric cancer data and facilitate deeper insights into pediatric cancer biology.

    The ScPCA Portal (https://scpca.alexslemonade.org/), developed and maintained by Alex’s Lemonade Stand Foundation (ALSF), is a data resource for single-cell and single-nuclei RNA sequencing data of pediatric tumors. The ScPCA Portal currently contains summarized gene expression data for over 700 samples from a diverse range of over 50 cancer types, all uniformly processed with an open-source workflow. All data on the portal is publicly available and ready for download in formats compatible with popular single-cell data analysis frameworks.

    To coordinate further analysis of the ScPCA data, we launched the OpenScPCA project in April 2024. The project aims to engage a broad community of researchers analyzing genomic data from pediatric tumors, building off the previous success of the Open Pediatric Brain Tumor Atlas project (Shapiro et al. 2023). As part of the OpenScPCA project, ALSF offers contributors technical guidance, comprehensive documentation, and access to computational resources.

    We invite researchers with expertise in pediatric cancer gene expression and single-cell RNA-seq analysis to join the OpenScPCA project. We hope those participating will discover new datasets to advance their research, gain experience with cutting-edge technologies, build their research portfolios, and join a supportive community. Get started at https://openscpca.readthedocs.io/en/latest/.
  abstract_title_: 'The Open Single-cell Pediatric Cancer Atlas project: Collaborative analysis of pediatric tumor data '
  email_address_: jaclyn.taroni@ccdatalab.org
  institution_: "Childhood Cancer Data Lab, Alex's Lemonade Stand Foundation"
  presenting_author_: 'Jaclyn N. Taroni'