Childhood Cancer Data Initiative Annual Symposium (Abstract Registration): Submission #34

Submission information
Submission Number: 34
Submission ID: 147985
Submission UUID: 5d3174b0-7f9a-4ec8-8d76-9dc04b0a829f

Created: Mon, 08/04/2025 - 14:12
Completed: Mon, 08/04/2025 - 14:14
Changed: Mon, 08/04/2025 - 14:14

Remote IP address: 10.208.28.82
Submitted by: Anonymous
Language: English

Is draft: No
Abstract Title: The Open Single-cell Pediatric Cancer Atlas project: Collaborative analysis of pediatric tumor data
Abstract: The Open Single-cell Pediatric Cancer Atlas (OpenScPCA) project is an open, collaborative initiative to analyze publicly available data from the Single-cell Pediatric Cancer Atlas (ScPCA) Portal. The goal of OpenScPCA is to enhance the utility of single-cell pediatric cancer data and facilitate deeper insights into pediatric cancer biology.

The ScPCA Portal (https://scpca.alexslemonade.org/), developed and maintained by Alex’s Lemonade Stand Foundation (ALSF), is a data resource for single-cell and single-nuclei RNA sequencing data of pediatric tumors. The ScPCA Portal currently contains summarized gene expression data for over 700 samples from a diverse range of over 50 cancer types, all uniformly processed with an open-source workflow. All data on the portal is publicly available and ready for download in formats compatible with popular single-cell data analysis frameworks.

To coordinate further analysis of the ScPCA data, we launched the OpenScPCA project in April 2024. The project aims to engage a broad community of researchers analyzing genomic data from pediatric tumors, building off the previous success of the Open Pediatric Brain Tumor Atlas project (Shapiro et al. 2023). As part of the OpenScPCA project, ALSF offers contributors technical guidance, comprehensive documentation, and access to computational resources.

We invite researchers with expertise in pediatric cancer gene expression and single-cell RNA-seq analysis to join the OpenScPCA project. We hope those participating will discover new datasets to advance their research, gain experience with cutting-edge technologies, build their research portfolios, and join a supportive community. Get started at https://openscpca.readthedocs.io/en/latest/.
Abstract:
Authors:
  1. First Name: Joshua
    Middle Initial: A
    Last Name: Shapiro
    Organization: Alex's Lemonade Stand Foundation
  2. First Name: Stephanie
    Middle Initial: J
    Last Name: Spielman
    Organization: Alex's Lemonade Stand Foundation
  3. First Name: Allegra
    Middle Initial: G
    Last Name: Hawkins
    Organization: Alex's Lemonade Stand Foundation
  4. First Name: Deepashree
    Last Name: Venkatesh Prasad
    Organization: Alex's Lemonade Stand Foundation
  5. First Name: Jennifer
    Last Name: O'Malley
    Organization: Alex's Lemonade Stand Foundation
  6. First Name: David
    Middle Initial: S
    Last Name: Mejia
    Organization: Alex's Lemonade Stand Foundation
  7. First Name: Jaclyn
    Middle Initial: N
    Last Name: Taroni
    Organization: Alex's Lemonade Stand Foundation
Presenting Author: Jaclyn N. Taroni
Institution: Childhood Cancer Data Lab, Alex's Lemonade Stand Foundation
Email Address: jaclyn.taroni@ccdatalab.org