Annual Meeting of the NCI Cohort Consortium (Abstract Submission): Submission #16

Lightning Talks Abstract
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Presenter's First Name: : Liliana









Presenter's Last Name:: Gomez-Flores-Ramos









Title (eg: professor, assistant professor, chair, etc):: Proffesor









Degree(s): Ph.D.









Contact Email:: liliana.gomez@insp.mx









Organization:: CONAHCyT – Center for Research on Population Health, National Institute of Public Health, Cuernavaca, Morelos, Mexico









Project Title:: Leveraging existing cohort studies of Mexican women to better understand Hispanic health









Additional Authors:
1. First Name: Dalia
   Last Name: Stern
   Degree(s): Ph.D.
   Organization: CONAHCyT – Center for Research on Population Health, National Institute of Public Health, Cuernavaca, Morelos, Mexico
2. First Name: Liliana
   Last Name: Gomez-Flores-Ramos
   Degree(s): Ph.D.
   Organization: CONAHCyT – Center for Research on Population Health, National Institute of Public Health, Cuernavaca, Morelos, Mexico
3. First Name: Briton
   Last Name: Trabert
   Degree(s): Ph.D.
   Organization: Department of Obstetrics and Gynecology, University of Utah, and Huntsman Cancer Institute at the University of Utah, Salt Lake City, UT, USA.
4. First Name: Loïc
   Last Name: Loïc Le Marchand
   Degree(s): Ph.D.
   Organization: University of Hawaii Cancer Center, Honolulu, HI, USA.
5. First Name: Henry
   Last Name: Gomez
   Degree(s): Ph.D.
   Organization: Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
6. First Name: Paul
   Middle Initial: A
   Last Name: Scheet
   Degree(s): Ph.D.
   Organization: Department of Population and Public Health Sciences, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
7. First Name: Martin
   Last Name: Lajous
   Degree(s): M.D., DPH
   Organization: Center for Research on Population Health, National Institute of Public Health, Cuernavaca, Morelos, Mexico and Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
8. First Name: V Wendy
   Last Name: Setiawan
   Degree(s): Ph.D.
   Organization: Department of Population and Public Health Sciences, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
9. First Name: Humberto
   Last Name: Parada Jr.
   Degree(s): Ph.D.
   Organization: Division of Epidemiology and Biostatistics, School of Public Health, San Diego State University, San Diego, CA, USA.
10. First Name: Amber
    Last Name: Prizada
    Degree(s): Ph.D. 
    Organization: University of Illinois at Chicago 
11. First Name: Leslie
    Middle Initial: V
    Last Name: Farland
    Degree(s): Ph.D.
    Organization: Department of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ, USA.










Abstract::
Background: The underrepresentation of Hispanics in epidemiologic research is a significant gap in our understanding of health disparities. We aimed to compare the distribution of cancer risk factors among Hispanic women of Mexican heritage (HWMH) participating in existing cohorts to explore the possibility of future data-pooling efforts.

Methods: We used baseline data of HWMH from three US-based studies, the Mexican American Cohort (MAC; n=19,797; 2001-17), the Multiethnic Cohort (MEC; n=18,007; 1993-96), and the Hispanic Community Health Study/Study of Latinos (HCHS/SOL; n=4,022; 2008-2011), and one from Mexico, the Mexican Teachers’ Cohort (MTC; n=115,275; 2006-08). 

Results: Participants in MEC (60y) were older on average than MAC (41y), HCHS/SOL (46y), and MTC (43y) at enrollment. Most MAC (78%) and HCHS/SOL (85%) participants spoke Spanish as their primary language. Age at menarche (13y), age at menopause (46-48y), and smoking prevalence (~10%) were similar across studies. Parity was higher in MAC (3.8) and MEC (4.1) compared to HCHS/SOL (3.2) and the MTC (2.5). Ever use of oral contraceptives was more frequent in HCHS/SOL (64%) compared to MTC (46%), MAC (38%), and MEC (35%). Obesity, diabetes, and hypertension were more common in the US cohorts. 

Conclusion: This work demonstrates the ability to pool NCI Cohort Consortium data to evaluate cancer risk factors in HWMH, an underrepresented group in cancer research. Similarities and differences in characteristics across cohorts can be leveraged to better understand health disparities in HWMH.