Annual Meeting of the NCI Cohort Consortium (Abstract Submission): Submission #16

Submission information
Submission Number: 16
Submission ID: 127592
Submission UUID: eea54fe5-fe1c-48ce-880c-cf06b9936533

Created: Fri, 09/13/2024 - 19:24
Completed: Fri, 09/13/2024 - 19:38
Changed: Fri, 09/13/2024 - 19:38

Remote IP address: 10.208.28.69
Submitted by: Anonymous
Language: English

Is draft: No
Lightning Talks Abstract
Liliana
Gomez-Flores-Ramos
Proffesor
Ph.D.
CONAHCyT – Center for Research on Population Health, National Institute of Public Health, Cuernavaca, Morelos, Mexico
Leveraging existing cohort studies of Mexican women to better understand Hispanic health
  1. First Name: Dalia
    Last Name: Stern
    Degree(s): Ph.D.
    Organization: CONAHCyT – Center for Research on Population Health, National Institute of Public Health, Cuernavaca, Morelos, Mexico
  2. First Name: Liliana
    Last Name: Gomez-Flores-Ramos
    Degree(s): Ph.D.
    Organization: CONAHCyT – Center for Research on Population Health, National Institute of Public Health, Cuernavaca, Morelos, Mexico
  3. First Name: Briton
    Last Name: Trabert
    Degree(s): Ph.D.
    Organization: Department of Obstetrics and Gynecology, University of Utah, and Huntsman Cancer Institute at the University of Utah, Salt Lake City, UT, USA.
  4. First Name: Loïc
    Last Name: Loïc Le Marchand
    Degree(s): Ph.D.
    Organization: University of Hawaii Cancer Center, Honolulu, HI, USA.
  5. First Name: Henry
    Last Name: Gomez
    Degree(s): Ph.D.
    Organization: Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
  6. First Name: Paul
    Middle Initial: A
    Last Name: Scheet
    Degree(s): Ph.D.
    Organization: Department of Population and Public Health Sciences, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
  7. First Name: Martin
    Last Name: Lajous
    Degree(s): M.D., DPH
    Organization: Center for Research on Population Health, National Institute of Public Health, Cuernavaca, Morelos, Mexico and Global Health and Population, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
  8. First Name: V Wendy
    Last Name: Setiawan
    Degree(s): Ph.D.
    Organization: Department of Population and Public Health Sciences, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA.
  9. First Name: Humberto
    Last Name: Parada Jr.
    Degree(s): Ph.D.
    Organization: Division of Epidemiology and Biostatistics, School of Public Health, San Diego State University, San Diego, CA, USA.
  10. First Name: Amber
    Last Name: Prizada
    Degree(s): Ph.D.
    Organization: University of Illinois at Chicago
  11. First Name: Leslie
    Middle Initial: V
    Last Name: Farland
    Degree(s): Ph.D.
    Organization: Department of Epidemiology and Biostatistics, Mel and Enid Zuckerman College of Public Health, University of Arizona, Tucson, AZ, USA.
Background: The underrepresentation of Hispanics in epidemiologic research is a significant gap in our understanding of health disparities. We aimed to compare the distribution of cancer risk factors among Hispanic women of Mexican heritage (HWMH) participating in existing cohorts to explore the possibility of future data-pooling efforts.

Methods: We used baseline data of HWMH from three US-based studies, the Mexican American Cohort (MAC; n=19,797; 2001-17), the Multiethnic Cohort (MEC; n=18,007; 1993-96), and the Hispanic Community Health Study/Study of Latinos (HCHS/SOL; n=4,022; 2008-2011), and one from Mexico, the Mexican Teachers’ Cohort (MTC; n=115,275; 2006-08).

Results: Participants in MEC (60y) were older on average than MAC (41y), HCHS/SOL (46y), and MTC (43y) at enrollment. Most MAC (78%) and HCHS/SOL (85%) participants spoke Spanish as their primary language. Age at menarche (13y), age at menopause (46-48y), and smoking prevalence (~10%) were similar across studies. Parity was higher in MAC (3.8) and MEC (4.1) compared to HCHS/SOL (3.2) and the MTC (2.5). Ever use of oral contraceptives was more frequent in HCHS/SOL (64%) compared to MTC (46%), MAC (38%), and MEC (35%). Obesity, diabetes, and hypertension were more common in the US cohorts.

Conclusion: This work demonstrates the ability to pool NCI Cohort Consortium data to evaluate cancer risk factors in HWMH, an underrepresented group in cancer research. Similarities and differences in characteristics across cohorts can be leveraged to better understand health disparities in HWMH.