Annual Meeting of the NCI Cohort Consortium (Abstract Submission): Submission #12

serial: '12'
sid: '127577'
uuid: 7f5d9978-95b5-4d53-8853-a6249d46acac
uri: /egrp/cohortconsortium/abstracts
created: '1726251885'
completed: '1726257744'
changed: '1726257744'
in_draft: '0'
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langcode: en
webform_id: cohort_2024_abstracts_submission
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data:
  additional_authors:
    - add_author_degree: Ph.D.
      add_author_first_name: Michael
      add_author_last_name: Cook
      add_author_middle: B
      add_author_organization: 'Our Future Health'
    - add_author_degree: 'M.B.B.S. MPH Sc.D.'
      add_author_first_name: David
      add_author_last_name: Hunter
      add_author_middle: J
      add_author_organization: 'University of Oxford; Our Future Health'
    - add_author_degree: 'M.D. MPH'
      add_author_first_name: Raghib
      add_author_last_name: Ali
      add_author_middle: ''
      add_author_organization: 'Our Future Health'
  degree_s_: Ph.D.
  email: Ben.Cairns@ourfuturehealth.org.uk
  first_name: Benjamin
  last_name: Cairns
  organization: 'Our Future Health'
  poster_title: 'Our Future Health: A New Prospective Cohort for Translational Research'
  short_biography_: |-
    Background: Our Future Health is a new UK-wide prospective cohort study supported by the UK Government, industry and charity sectors. Our objective is to recruit 5 million adult residents of the UK to facilitate aetiologic and translational health research, aiming to discover and test more effective approaches to prevention, earlier detection and treatment of diseases. 

    Methods: The sampling frame for Our Future Health is the total UK adult population. Through invitations and open enrolment, we aim to recruit a cohort that reflects the diversity of the UK population in terms of age, ethnicity, socioeconomic status and geography. Participants complete a questionnaire and attend an appointment for physical measurements and blood sampling, and are genotyped using a custom array with a genome-wide backbone for imputation and extensive coverage of disease- and phenotype-associated variants. Priority data linkages include primary and secondary care records, and cancer and death registrations, in each of the four UK nations.

    Results: To date, 1.8 million participants have consented to join Our Future Health, of which 1.3 million have completed the broad baseline questionnaire and over 1 million have donated blood for genotyping and biobanking of plasma, buffy coat and DNA.

    Discussion: Key translational aspects of the study include the forthcoming ability for study proposals to request access to baseline blood samples, and for investigator-led recontact studies to recruit participants based on demographics, phenotypes, genotypes or disease risk for risk-stratified research. Our Future Health (ourfuturehealth.org.uk) is already open for data access study proposals.
  title: Dr