Hidden in Plain Sight (HIPS): The Role of Organelles in Cancer Biology (Registration)

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Registration

Registration for the Webinar Series on Hidden in Plain Sight (HIPS): The Role of Organelles in Cancer Biology is free and open to the public. The webinar will be is virtual public participation only. Advance registration is encouraged. Filling out this form registers you for sessions 2-4 in this webinar series. After receiving the registration confirmation email, you will have the option to save the webinars to your calendar.

 

OMB No.: 0925-0740
Expiration Date: 11/30/2028

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Session 1: Fueling the Tumor — Organelles at the Heart of Metabolic Reprogramming and Stress Adaptation
Metabolic reprogramming in cancer extends far beyond the Warburg effect. This session will explore how mitochondria, lysosomes, lipid droplets, and the endoplasmic reticulum work together to reshape cellular metabolism, manage stress, and enable tumor cells to adapt and survive under challenging conditions.
Moderator: Roberto Zoncu, UC Berkeley
Presenter 1: Greg Delgoffe, University of Pittsburg
Presenter 2: Kay Macleod, University of Chicago
Session 2: Lost in Translation — Organelle Crosstalk and Membrane Contact Sites in Cancer
Organelles do not function in isolation; they form dynamic physical contacts that facilitate lipid transfer, calcium signaling, and metabolic coordination. This session examines how tumor cells exploit inter-organelle communication to adapt to cellular stress and modulate innate immune responses through crosstalk among the mitochondria, ER, Golgi, and lysosomes.
Moderator: Orian Shirihai, UCLA
Presenter 1: Kevin Foskett, University of Pennsylvania
Presenter 2: Costas A. Lyssiotis, University of Michigan
Session 3: Context Is Everything — Studying Organelle Biology Across Tumor Types, Microenvironments, and Disease States
Organelle identity and function are highly dynamic, shaped by tumor type, disease stage, and the surrounding microenvironment. This session will explore how organelle biology varies across different cancer contexts, the experimental models best suited to capture this complexity, and how these differences influence the design and interpretation of cancer research.
Moderator: Rushika Perera, University of California, San Francisco
Presenter 1: Matt Vander Heiden, Massachusetts Institute of Technology
Presenter 2: Christie Towers, Salk Institute
Session 4: Seeing Is Believing — Emerging Tools and Technologies for Studying Organelles in Cancer
Advances in technology are transforming how we study organelles in cancer cells. This session will highlight emerging approaches—including organelle immunoprecipitation, proximity labeling, spatial proteomics, and STORM imaging—and how these tools are providing new insights into the mechanisms that drive tumor initiation, adaptation, and metastasis.
Moderator: Lulu Ang Cambronne, University of Texas at Austin
Presenter 1: Kivanc Birsoy, Rockefeller University
Presenter 2: Margarida Barroso, Albany Medical College
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