Childhood Cancer Data Initiative Annual Symposium (Agenda)

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Agenda

Friday, September 18, 2026
8:00 a.m. – 8:45 a.m.Registration & Networking
8:45 a.m. – 8:50 a.m.Welcome, Introduce NCI Director
Speaker: Jack Shern, M.D.
8:50 a.m. – 9:00 a.m.Remarks from NCI Director 
Speaker: Anthony Letai, M.D.
9:00 a.m. – 9:15 a.m.CCDI: From Data to Discovery — Shaping the Future
Evolving the CCD Learning Ecosystem
Speaker: Warren Kibbe, Ph.D.
9:15 a.m. – 10:30 a.m.Data Generated: Standing on the Shoulders of Giants
Building the National Strategy
 Molecular Profiling of High-Risk Solid Malignancies Identifies Targeted Therapy Options  
Speaker: Katie Janeway, M.D.
 Molecular Characterization Initiative (MCI) Platform for Advancing Precision Diagnosis and Discovery in Pediatric CNS Tumors
Speaker: Diana Thomas, M.D., Ph.D. and Sarah Leary, M.D., M.S.
 Germline Cancer Predisposition in the MCI: Opportunities for Assessing Outcomes and Promoting Cascade Testing
Speaker: Phil Lupo, Ph.D., MPH
 Sarcoma, the Imaging Data Commons and Research Characterization 
Speaker: Jack Shern, M.D.
10:30 a.m. – 10:45 a.m.Break
10:45 a.m. – 12:00 p.m.CCDI Data Ecosystem in Action; From Data to Discovery
Lightning Talks
 Use of Bulk FHIR EHR Data for Extracting and Abstracting Research-Relevant Content
Speaker: Hannah Calkins, MSIS
 From WSI to Methylation-Defined CNS Tumor Classes in the CCDI-MCI
Speaker: Rakesh Khanna
 Multicenter Histology Image Integration For Machine Learning-enabled Pediatric Sarcoma Classification
Speaker: Jill Rubinstein, M.D., Ph.D.
 GAIPO: Graph Artificial Intelligence for Pediatric Oncology 
Speaker: Jing Su, Ph.D.
 Leveraging AI to Characterize Acute Leukemia
Speaker: Shibiao Wan, Ph.D.
 Building Real-World Data Sets with the ExtractEHR+ Toolkit
Speaker: Richard Aplenc, M.D., Ph.D., MSCE, and Tamara Miller M.D., MSCE
12:00 p.m. – 12:35 p.m.Advocate and Family Perspectives
Speakers: Ann Ramer, Scott Lenfestey; Ailani Myers; Stephanie McMahon
12:35 p.m. – 2:00 p.m.Lunch, Poster Session, and CCDI Resource Fair
2:00 p.m. – 3:15 p.m.Towards the Integrated Learning Health System
 Survivorship and Patient-Mediated Data Sharing
Speaker: Brian Furner, M.S.
 RADIANT, PCX, and MCI: Piloting Tools, Workflows, and Collaborative Frameworks for Scaled National Infrastructure on Behalf of Clinical Research
Speaker: Adam Resnick, Ph.D.
 RADIANCE (Rapid AI for Data Integration and Analytics in Childhood and Young Adult Cancer Ecosystems)
Speaker: Heidi Hanson, Ph.D.
 The Role of Cancer Registries in the Learning Health Systems -- Perspectives from the NCCR
Speaker: Betsy Hsu, Ph.D., MPH
 Childhood Cancer Data Initiative Federation API: Facilitate Data Discovery Across Resources
Speaker: Subhashini Jagu, Ph.D. 
3:15 p.m. – 3:30 p.m.Break
3:30 p.m. – 4:30 p.m.Fireside Chats – Looking Ahead
 Fireside Chat 1: Accelerating Therapeutic Development in Pediatric Oncology
Participants: Stacey Adam, Ph.D.; Diana Bradford, M.D.; Rosandra Kaplan, M.D., Jack Shern, M.D.
 Fireside Chat 2: AI Applications in the Clinic
Participants: Frank Alexander, Ph.D.; Julian Hong, M.D.; Warren Kibbe, Ph.D.; Elaine Mardis, M.D.
4:30 p.m. – 5:00 p.m.Engaging with CCDI, NIH, and Next Steps         
 Pediatric and AYA Challenges and Highlighted Topics
Jaime Guidry Auvil, Ph.D.
 NIH Biogenesis Mission and HHS APG Goals
Speaker: Warren Kibbe, Ph.D.
5:00 p.m.Adjourn