Annual CCR and DCEG Staff Scientists and Staff Clinicians Retreat (Agenda)

Agenda

20th Annual CCR and DCEG Staff Scientists and Staff Clinicians Retreat 
“Interdisciplinary Collaborations in Cancer Research”

Date: Friday, April 26, 2024

Location: NCI Shady Grove Campus

9609 Medical Center Drive 

Rockville, MD 20850 

Joseph F. Fraumeni Jr., M.D. Conf. Rm TE406/408/410

 

8:45-9:00 a.m. Registration and posters setup
9:00-9:15 a.m. Welcome address by Dr. Stephen Chanock, Director, DCEG
Moderator: Dr. Duane Hamilton
9:15-9:30 a.m. NCI Director’s remarks by Dr. Kimryn Rathmell
Moderator: Dr. Brajendra Tripathi
9:30-10:15 a.m. Keynote address I by Dr. Frank McCormick (UCSF)
Moderator: Dr. Brajendra Tripathi
Title: RAS proteins in human disease
10:15-10:25 a.m. Coffee break for 10 min
10:25-11:25 a.m.

Oral Presentation Session I: SS/SC selected speakers
Moderators: Dr. Brajendra Tripathi and Dr. Zhihui Liu

Dr. Bing-Rui Zhou
Title: Pioneer transcription factors Ascl1/E12a and TFAP2a use distinct modes of nucleosome binding to expose DNA in chromatin

Dr. Binwu Tang
Title: A novel imaging approach suggests a critical role for cancer stem cells as sensitive sensors of microenvironmental quality in metastatic progression

Dr. James Madigan
Title: Multiple layers of epigenetic regulation conspire to silence expression of somatostatin receptor type 2 in pancreatic neuroendocrine tumors

Dr. James Phelan
Title: Response to BTK inhibitors in aggressive lymphomas linked to chronic selective autophagy
11:25 a.m.-11:30 a.m. Staff Scientists Organization Introduction by Dr. Swati Choksi
11:30 a.m.-12:15 p.m. Poster Session I (odd numbered abstracts)
12:15-1:15 p.m. Lunch and small group discussions
1:15-2:00 p.m. Poster Session II (even numbered abstracts)
2:00-2:45 p.m. Keynote address II by Dr. Tyler Jacks (MIT)
Moderator: Dr. Duane Hamilton
Title: Investigating tumor-immune dynamics using genetically engineered mouse models of cancer
2:45-3:00 p.m. Coffee break for 15 min
3:00-3:45 p.m.

Oral Presentation Session II: SS/SC selected speakers
Moderators: Dr. Brajendra Tripathi and Dr. Zhihui Liu

Dr. Sofia Gameiro
Title: Harnessing the potential of epigenetic modulation in combination with tumor-targeted IL-12 to overcome tumors refractory to PD-1/-L1-targeted therapy

Dr. David Milewski
Title: Engineered adoptive T cell transfer in combination with TGF- beta signaling blockade for immunotherapy against osteosarcoma and other malignancies

Dr. Dimitris Stellas
Title: Combination treatment of hetIL-15 and Fenofibrate affects the metabolic fitness of tumor infiltrating CD8+T cells, severely impacting tumor growth in breast and pancreatic cancer mouse models
3:45-4:30 p.m.

Oral Presentations Session III: SS/SC Selected speakers
Moderators: Dr. Duane Hamilton and Dr. Sukhbir Kaur

Dr. Lene Veiga
Title: Thoracic soft tissue sarcoma risk following breast cancer treatment in two US retrospective cohorts

Dr. Masashi Watanabe
Phase II trial evaluating the association of peripheral blood immunologic response and therapeutic response to immune checkpoint inhibition in patients with newly diagnosed glioblastoma and gliosarcoma

Dr. Stacy Doran
Tumor-Infiltrating Lymphocytes (TIL) for Metastatic Human Papillomavirus (HPV)-Associated Cancers
4:30-4:45 p.m.

Ms. Sue Scott
Cancer survivorship speaker (Office of Advocacy Relations) Moderator: Dr. Duane Hamilton
4:45-5:00 p.m.

Awards ceremony and closing remarks by Dr. James Gulley, Clinical Director, CCR
Moderator: Dr. Brajendra Tripathi
5:30-8:00 p.m.

Happy hour at Rio Lakefront, Gaithersburg, Maryland
(in front of Uncle Julio’s tavern)