CCP - In the Know (Past Webinars)

Past Webinars


  Monday, March 20, 2023 | 3 to 4 pm EST

Genetic Ancestry and Breast Cancer Disparities
Brittany Lord, PhD, MPH, MS

How do our genetics impact our breast cancer risk? Black women are 40% more likely to die from breast cancer, but the reasons are multi-faceted. This includes genetic and socioeconomic contributors that worsen breast cancer outcomes for Black women. In this seminar, Dr. Lord will discuss the use of genetic ancestry in cancer research, as well as discuss an ancestrally informative genetic marker that is more commonly found in Black women, potentially impacting their breast cancer outcomes.

Dr. Brittany Lord is a Cancer Prevention Fellow working with Dr. Stefan Ambs in the Center for Cancer Research and Dr. Gretchen Gierach in the Division of Cancer Epidemiology and Genetics. Dr. Lord’s work focuses on understanding breast cancer disparities and the contribution of genetic ancestry to disease risk, in addition to investigating epidemiologic risk factors for breast cancer in diverse populations. Dr. Lord’s research and efforts are a prime example of how inclusion of diverse ethnic groups can enrich study designs and broaden the impact of study results to underserved populations.

Presentation Recording

  Thursday, May 18, 2023 | 3 to 4 pm EST

CRISPR-Cas9 Gene Editing
Theodore Busby III, PhD

What is CRISPR and how is this technology being used? CRISPR-based technologies have helped to make large strides in the field of biomedical sciences. These strategies have also been applied in agriculture for improving the quality of crops. In this seminar, Dr. Busby will discuss the use of CRISPR-based gene editing in biomedical research and some of the potential outcomes of this technology in health and agriculture.

Dr. Theodore Busby is a postdoctoral fellow with Dr. Tom Misteli in the Laboratory of Receptor Biology and Gene Expression in the Center for Cancer Research. Dr. Busby’s research investigates the arrangement of DNA in the 3-dimensional space of the cell nucleus and how this regulates cancer related gene expression. Using microscopy to generate images of the genome, these studies will allow us to understand how specific events cause changes to chromosome structure in individual cells across a population of tumor cells.

Presentation Recording

  Wednesday, June 28, 2023 | 3 to 4 pm EST

Demystifying the Tumor Microenvironment: How Cancer Gets by with a Little Help from its Friends
Alexandra R. Harris, Ph.D., M.P.H., M.S.

Did you know that cancer can manipulate its surrounding environment to help it grow and spread? Each tissue in the body is made up of unique cellular elements and biophysical forces – a “microenvironment”. As cancer begins, grows, and spreads within and beyond a tissue, the microenvironment it interacts with along the way can respond by either inhibiting or promoting the tumor. In this seminar, Dr. Harris will introduce key components of the tumor microenvironment, the role they play in tumor initiation and progression, and the implications for therapy.

Dr. Alexandra Harris is a Cancer Prevention Fellow at the National Cancer Institute working with Dr. Gretchen Gierach in the Division of Cancer Epidemiology and Genetics and Dr. Stefan Ambs in the Center for Cancer Research. Dr. Harris’ work aims to characterize how factors like genetic ancestry, the environment, and other epidemiologic risk factors can impact the microenvironment in breast cancer in diverse populations. Her work then aims to connect microenvironmental signatures to tumor biology, cancer outcomes, and disparities, with the eventual hope of informing therapy to benefit patients equitably.

Presentation Recording