Agenda
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DRAFT AGENDA
DAY 1, September 28th: (11:00 AM to 4:30 PM)
| 11:00–11:10 AM | Welcome Altaf Mohammed, Ph.D., Meeting Co-Organizer, DCP/NCI Brian Cholewa, Ph.D., Meeting Co-Organizer, DCP/NCI |
| 11:10–12:00 PM | Plenary Talk Lori Minasian, MD., Deputy Director, DCP/NCI NCI Division of Cancer Prevention: Overview and Research Opportunities |
Session I: Emerging Targets, Vaccines and Immunomodulatory Agents for Cancer Prevention | |
| Co-Chairs: Nicholas Arpaia and Anda Vlad | |
| 20 minutes talk, 10 min Q&As | |
| 12:00–12:30 PM | LungVax vaccine for lung cancer prevention Speaker 1: Sarah Blagdon, BSc, FRCP, PhD, University of Oxford |
| 12:30–1:00 PM | Programmable probiotics for personalized cancer immunotherapy and immunoprevention Speaker 2: Nicholas Arpaia, Ph.D., Columbia University Irving Medical Center |
| 1:00–1:30 PM | Lunch |
| 1:30–2:00 PM | Immune determinants modulating cancer development in Lynch Syndrome Speaker 3: Robert Samstein, MD, Ph.D., Icahn School of Medicine at Mount Sinai |
| 2:00–2:30 PM | Targeting the A2B Adenosine Receptor for Immunoprevenion of Pancreatic Cancer Speaker 4: Jennifer Bailey, Ph.D., University of Texas HSC Houston |
| 2:30–3:00 PM | Manufacture of Epstein-Barr Virus Vaccine Speaker 5: McGuire, Andrew, PhD, Fred Hutchinson Cancer Center |
| 3:00–3:30 PM | Break |
| 3:30–4:30 PM | Early Investigator Flash Talks |
| Co-Chairs: Altaf Mohammed and John Clifford | |
| 10 minutes talk, 5 min Q&As | |
| 3:30–3:45 PM | ONC201 for Colorectal Cancer Prevention Speaker 1: Alexander Raufi, MD |
| 3:45–4:00 PM | Caloric restriction enhances the function of the immune system Speaker 2: Nicholas Collins, Ph.D., Weill Cornell Medicine |
| 4:00–4:15 PM | The Perfect Pair: Engineering Drug Synergy and Nano Drug Delivery Precision for Smarter Cancer Prevention Speaker 3: Preshita P. Desai, B. Pharm, PhD; Western University of Health Sciences |
| 4:15–4:30 PM | Bladder cancer prevention Speaker 4: Venkateshwar Madka, Ph.D., University of Oklahoma |
| Adjourn | |
DAY 2, September 29th: (11:00 AM to 5:00 PM)
Session II: Molecularly Targeted Novel Agents for Cancer Prevention and Interception | |
| Co-Chairs: Michael Buszczak and Asad Umar | |
| 20 minutes talk, 10 min Q&As | |
| 11:00–11:30 AM | Investigating novel targets for topical immunoprevention of skin cancer Speaker 1: Clara Curiel, MD., University of Arizona |
| 11:30–12:00 PM | Mitochondria-targeted honokiol for lung cancer interception Speaker 2: Ming You, M.D., Ph.D., Houston Methodist Research Institute |
| 12:00–12:30 PM | Discovery and Development of Natural Products for Liver Cancer Prevention Speaker 3: Michael Buszczak, Ph.D., UT Southwestern Medical Center |
| 12:30–1:00 PM | TBD Speaker 4 |
| 1:00–1:30 PM | LFA9 for Colon Cancer Prevention and Interception: Discovery to Clinic Speaker 5: Chinthalapally V. Rao, Ph.D., University of Oklahoma |
| 1:30–2:00 PM | Lunch |
Session III: Clinically relevant alternative models for cancer prevention | |
| Co-Chairs: Brian Cholewa and Kajal Biswas | |
| 20 minutes talk, 10 min Q&As | |
| 2:00–2:30 PM | Organoids for Cancer Prevention, Interception and Treatment Speaker 1: David Tuveson, PhD, Cold Spring Harbor Laboratory |
| 2:30–3:00 PM | Microfluidics in biomedical research: lab-on-a-chip microtechnologies Speaker 2: David Beebe, Ph.D. University of Wisconsin |
| 3:00–3:30 PM | NAMs and drug screening Speaker 3: Joseph C. Wu, MD, PhD., Stanford University School of Medicine |
| 3:30–4:00 PM | Organoids for cancer prevention Speaker 4: Yurong Song. PhD., Leidos |
| 4:00–5:00 PM | Meet with the NCI Program Staff
|
| Adjourn | |
DAY 3, September 30th: (11:00 AM to 4:30 PM)
Session V: Cancer Prevention-Interception Clinical Trials | |
| Co-Chairs: Eduardo Vilar-Sanchez and Goli Samimi | |
| 20 minutes talk, 10 min Q&As | |
| 11:00–11:30 AM | Overview of DCP Supported Clinical Trials Speaker 1: Goli Samimi, Ph.D., DCP/NCI |
| 11:30–12:00 PM | Nous 209 vaccine trial Speaker 2: Eduardo Vilar-Sanchez, MD, Ph.D., MD Anderson Cancer Center |
| 12:00–12:30 PM | RENAISSANCE trial for breast cancer prevention Speaker 3: Seema Khan, MD, Northwestern Feinberg School of Medicine |
| 12:30–1:00 PM | Apalutamide low dose trial for prostate cancer prevention Speaker 4: Juan Chipollini, MD; The University of Arizona |
| 1:00–1:30 PM | Daily Exemestane in Women with Endometrial Intraepithelial Neoplasia or Low Grade Endometrial Cancer Speaker 5: Britt K Erickson, MD; University of Minnesota |
| 1:30–2:00 PM | Break |
Session IV: Panel Discussion | |
| Biomarkers as intermediate end points for cancer prevention clinical trials | |
| Co-Chairs: Brandy Heckman-Stoddard | |
| 2:00–2:25 PM | TBD |
| 2:25–2:50 PM | Status on current intermediate end points for cancer prevention clinical trials Brandy Heckman-Stoddard, Ph.D., DCP/NCI |
| 2:50–4:30 PM | Panel Discussion |
| Closing Remarks and Adjourn Brian Cholewa, Ph.D., Meeting Co-Organizer, DCP/NCI Altaf Mohammed, Ph.D., Meeting Co-Organizer, DCP/NCI | |