NCI Emerging Technologies Seminar Series (Registration)

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Registration

Please use the form below to register for the upcoming NCI Emerging Technologies Seminar Series.

 

OMB No.: 0925-0740
Expiration Date: 9/30/2025

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Seminar Selections

Select all upcoming seminars you would like to attend:

Title: Uncovering new predictive markers in cancer research with novel tools that define the molecular pathology of the extracellular microenvironment
Speaker: Peggi Angel, Ph.D., Medical University of South Carolina.
Content: Dr. Angel will describe how her lab has developed novel tools and workflows to target the extracellular microenvironment from clinically archived tissues. She will discuss tool development and ongoing work to understand how the extracellular proteome, including post translational modifications, contributes to cancer progression.

Title: Proximity Barcoding Chemoproteomic Platforms to Map and Manipulate Oncogenic Signaling
Speaker: Raymond Moellering, Ph.D., University of Chicago.
Content: Dr. Moellering will present novel chemical probes and proteomic technologies developed in his lab to expose and exploit signaling mechanisms in cancer and other diseases.

Title: Viscoelasticity and Cancer.
Speaker: David Mooney, Ph.D., Wyss Institute, Harvard University.
Content: Dr. Mooney will describe new biomaterial technologies developed in his lab to manipulate cell function, understand how cells sense their physical environment, and recruit and re-educate the immune system to destroy cancer cells.

Title: Finding neighborhoods in the land of spatial omics
Speaker: Kai Tan, Ph.D., Children’s Hospital of Philadelphia & University of Pennsylvania.
Content: Dr. Tan will talk about the single cell spatial-omics informatics tool CytoCommunity, which is designed to identify condition-specific cellular clusters in tissue for interpretation of cell function and cell-cell communication.

Title: DNA origami vaccine (DoriVac) for cancer and infectious diseases
Speaker: Yang Claire Zeng, M.D., Ph.D., Wyss Institute and Dana Farber Cancer Institute
Content: During this seminar, Dr. Zeng will describe a DNA origami vaccine platform called DoriVac. The approach allows delivery of both the antigen and the adjuvant on the same particle, allowing them to work together to create a very strong and selective immune response, as well as promoting long-term memory to prevent cancer from returning. June 25 2024 2:00-3:00pm ET

Title: Representing and Embedding Tissue Structures
Speaker: Dana Pe'er, Ph.D., Memorial Sloan Kettering Cancer Center
Content: Dr. Pe'er will share about new bioinformatics tools to explore the complex tumor microenvironment as part of the Cancer Moonshot Human Tumor Atlas Network.

Speaker 1: Ino de Bruijn, Memorial Sloan Kettering Cancer Center
Title 1: Exploring Multimodal Cancer Data via cBioPortal and the HTAN Portal
Speaker 2: Erin Wissler Gerdes, University of Iowa
Title 2: Evaluating Usability and Feasibility of Implementing Cancer Epidemiology Maps for SEER Registry End Users
Content: During this seminar, two early career researchers will share about new informatics tools they're developing to advance cancer research. Ino de Bruijn will share about the HTAN Data Portal and the open source cBioPortal tool for visualization, analysis, and download of cancer genomics data being developed in Dr. Nikolaus Schultz's lab. Erin Wissler Gerdes will present on the implementation, evaluation, and usability of an interactive risk mapping tool to estimate cancer rates and risk in small geographic regions being developed in Dr. Jacob Oleson's lab.

Title: Detecting and characterizing the structure of extrachromosomal DNA
Speaker: Vineet Bafna, Ph.D., University of California, San Diego
Content: During this seminar, Dr. Bafna will describe new algorithms and forthcoming tools to serve the exciting field of extrachromosomal DNA (ecDNA). This includes the Community Accessible Pipeline for ecDNA Reconstruction (CAPER) platform to elucidate the structure, function, and evolution of ecDNA.

Title: Endosome-mitochondria interactions in breast cancer and metastasis
Speaker: Margarida Barroso, Ph.D., Albany Medical College
Content: At this seminar, Dr. Barroso will describe new imaging quantification methods that use the spatial context of organelles and their topology for cancer cell classification.

Title: Tools to Evaluate, Track, and Ensure the Integrity of Biospecimens
Speaker: Chad Borges, Ph.D., Arizona State University
Content: At this seminar Dr. Borges will describe new chemical approaches for tracking the exposure of biospecimens to thawed conditions, under which biochemical reactions occur that cause the specimens to no longer reflect in vivo reality at the molecular level.

Title: TBD
Speaker: Sofia Merajver, M.D., Ph.D., University of Michigan
Content: During this seminar, Dr. Merajver will share about the development of a microfluidic device that mimics the cellular and physical components of the human blood-brain niche to study the brain metastatic process, in particular how subclones of breast cancer compare in terms of their ability to extravasate, migrate, and survive in this niche.

Title: Dynamics of 3D Genome Structure and Function
Speaker: Anders Sejr Hansen, Ph.D., Massachusetts Institute of Technology
Content: During this seminar, Dr. Hansen will describe novel high-resolution tools developed in his lab to study 3D genome structure in time and space. In particular, he'll share how they have applied these tools to track the looping between DNA elements such as enhancers and promoters and study how dysregulation of these processes can cause oncogene overexpression in cancer.

Title: TBD
Speaker: José Mejía Oneto, M.D., Ph.D. and Travis Biechele, Ph.D., Shasqi Inc.
Content: At this seminar, Dr. Mejía Oneto and Dr. Biechele will discuss the development of Shasqi's Click-Activated Prodrugs Against Cancer (CAPAC) platform. CAPAC represents a novel approach to overcoming the limitations of many existing treatment approaches, such as antibody-drug conjugates. They will also describe recent successes showing how the platform has also been used to activate immune response against sarcomas.

Title: Mapping Tumor Heterogeneity Across Space and Time
Speaker: Ben Rapahel, Ph.D., Princeton University
Content: During this seminar, Dr. Raphael will describe computational methods developed in his lab to analyze tumor heterogeneity using genomics and spatial transcriptomics technologies. He will describe machine learning methods to investigate the tumor microenvironment and phylogenetic algorithms to study tumor evolution in 2D and 3D space. He will demonstrate applications of these open-source software tools to analyze data from multiple cancer types and molecular profiling technologies.

Title: Dynamics of 3D Genome Structure and Function
Speaker: Anders Sejr Hansen, Ph.D.
Content: During this seminar, Dr. Hansen will describe novel high-resolution tools developed in his lab to study 3D genome structure in time and space. In particular, he’ll share recent work focused on tracking the looping between DNA elements such as enhancers and promoters, how DNA looping affect transcription, and how dysregulation of these processes can cause oncogene overexpression in cancer.

Title: Pre-Targeting with in vivo Click Chemistry for Next-Gen ADCs and Targeted Radiotherapeutics (TRTs)
Speaker: José Mejía Oneto, M.D., Ph.D., and Travis Biechele, Ph.D., Shasqi Inc.
Content: During this seminar, Dr. Mejía Oneto and Dr. Biechele will share about the development of Shasqi’s Click-Activated Prodrugs Against Cancer (CAPAC) platform. CAPAC represents a novel approach to overcome the limitations of existing treatment approaches, such as antibody-drug conjugates. They will also describe recent successes showing how the platform has been used to activate immune response against sarcomas.

Title: Programs and Resources to Support Technology Development for Cancer Research
Speaker: Kelly Crotty, Ph.D., National Cancer Institute
Content: The National Cancer Institute (NCI) drives early-stage innovative technology development and translation of emerging tools into laboratory and clinical use through numerous programs focused on a specific field or phase of technology development. During this seminar, Dr. Kelly Crotty will share about the many programs and resources NCI has to support the development of highly innovative technologies to better understand, prevent, diagnose, and treat cancer to ultimately help people live longer and healthier lives.

Title 1: Multiplex, high-throughput method to study cancer and immune cell mechanotransduction
Speaker 1: Abigail Fabiano, Vanderbilt University and Rice University
Title 2: Adhesion Strength of Tumor Cells Predicts Metastatic Disease in vivo 
Speaker 2: Madison Kane, University of California San Diego
Content: During this seminar, two early career researchers will share about new mechanobiology tools they're developing to advance cancer research. Abigail Fabiano will share her work developing high-throughput, semi-automated methods using a commercially available pipetting device. These methodologies are designed to expose cells to physiological fluid sheer stress while processing a vast number of samples simultaneously, supporting the ability to study mechanoresponses of cells during cancer metastasis. Madison Kane will describe a novel label-free method using a parallel-plate flow chamber for assessing cell adhesion strength to evaluate this measure as a marker for metastatic potential.
Title 1: Imaging cancer across scales with self-driving, multi-scale microscopy
Speaker 1: Stephan Daetwyler, Ph.D., UT Southwestern Medical Center
Title 2: Expansion Microscopy of Lymphoma Organoids Reveal T Cell-Driven Epigenetic Modulation of Malignant B Cells
Speaker 2: Lucy Britto, Georgia Tech & Emory University
Content: During this seminar, two early career researchers will share about the new tools they’re developing to advance cancer research. Dr. Stephan Daetwyler will share about his work developing a multi-scale microscopy method to simultaneously observe and quantify subcellular dynamics in the context of entire organisms in vitro and in vivo over hours of imaging, and applying the platform to study developmental processes, cancer invasion, and metastasis. Lucy Britto will describe use of Expansion Microscopy (ExM) to study synthetic hydrogel-based lymphoma organoids to examine how aspects of the tumor microenvironment influence the clustering of histone methylation within diffuse large B cell lymphoma cells.