crs-eocrc (Overview)




In contrast to the dramatic decreased incidence rate of colorectal cancer (CRC) in older populations in the United States, incidence rates in younger adults are rapidly increasing and have more than doubled since the early 1990s. Early-onset (EO) CRC is defined as colon and rectal cancers diagnosed in persons less than 50 years of age. Younger patients are often diagnosed at a later stage of the disease, when it is more challenging to treat.

Supported by the National Cancer Institute (NCI) and National Institute of Environmental Health Sciences (NIEHS), this virtual think tank meeting will bring together national experts from inter-disciplinary fields to identify research priorities that address the important problems, barriers, and potential solutions surrounding EO-CRC. Potential environmental factors and biological mechanisms contributing to the increasing incidence of EO-CRC will be discussed.

This meeting is relevant to the current NCI Provocative Question 1: What are the underlying causes of the unexplained rising incidence in certain early-onset cancers?


Planning Committee:

  • Carmen Allegra, NCI
  • Laura Brockway-Lunardi, NCI
  • Phillip Daschner, NCI
  • Rao Divi, NCI
  • Roberto Flores, NCI
  • Tram Kim Lam, NCI
  • Xiaoling Li, NIEHS
  • Holli Loomans, NCI
  • Somdat Mahabir, NCI
  • Stefanie Nelson, NCI
  • Steve Nothwehr, NCI
  • Arun Pandiri, NIEHS
  • Les Reinlib, NIEHS
  • Gabriela Riscuta, NCI
  • Sharon Ross, NCI
  • Harold Seifried, NCI
  • Rashmi Sinha, NCI
  • James V. Tricoli, NCI
  • Asad Umar, NCI
  • Anil Wali, NCI
  • Matthew Young, NCI