Engaging Older Adults in the NCI Clinical Trials Network (Agenda)

Agenda

The accrual meeting will be held virtually on April 26-27, 2021 and is supported by Cancer MoonshotSM and coordinated by The NCI Division of Cancer Prevention in collaboration with the Division of Cancer Treatment and Diagnosis.

Objectives

  1. Identify modifiable barriers to the participation of older adult patients in cancer clinical trials, with an emphasis on reducing clinician bias, and develop actionable interventions to address barriers.
  2. Identify patient needs and concerns and develop and implement interventions to address those concerns.
  3. Build consensus around the best approach and measures to screen for fitness and frailty.
  4. Develop a broader research plan to guide the implementation of geriatric assessments in future NCI-supported clinical trials to address gaps in research.

 

DAY 1: April 26th, 11-4:45 p.m. EST

Time Topic Presenter/Moderator
11:00-11:10 a.m. Welcome

Philip E. Castle, PhD, MPH
Director, Division of Cancer Prevention

Worta McCaskill-Stevens, MD, MS.
Chief, Community Oncology and Prevention Trials Research Group
Director, NCI Community Oncology Research Program (NCORP)
Division of Cancer Prevention

Meg Mooney, MD, MS
Associate Director, CTEP
Branch Chief, Clinical Investigations Branch
11:10-11:15 a.m. Meeting Overview

Diane St. Germain, RN, MS

Supriya Mohile, MD, MS
11:15-11:30 a.m. Show Me the Numbers: NCI Accrual Data

Grace Mishkin, MPH

Diane St. Germain, RN, MS
11:30-11:45 a.m. Keynote Address: Closing the Evidence Gap for Older Adults: A Call to Action

Heidi Klepin, MD
11:45-1:15 p.m.

Trial Design Considerations to Increase Older Adult Accrual to Clinical Trials

Moderators:
Jennifer Le-Rademacher, PhD
Rich Little, MD

Stakeholder Response

Brea Lipe, MD
Karlynn BrintzenhofeSzoc, PhD
Jane Perlmutter, PhD

Discussion

ALL
1:15-1:45 p.m. BREAK

 
1:45-3:15 p.m.

Infrastructure to Support Accrual of Older Adults to Clinical Trials

Discussion Leads:
Mina Sedrak, MD, MS
Grace Mishkin, PhD

Moderator:
William Dale, MD, PhD

Additional Stakeholder Response

Christa Braun-Inglis, APRN

Discussion

ALL
3:15-4:15 p.m.

NCORP Provider Survey Results: Physician Bias

Judith Hopkins, MD

Explicit Benevolence as Geriatric Trial Accrual Mediator

Matt Hudson, PhD

Discussion

ALL
4:15-4:45 p.m. Recap of Day 1 and Selection of Topics for Discussion on Day 2

William Dale, MD, PhD
Heidi Klepin, MD
Supriya Mohile, MD, MS

 

DAY 2, April 27th, 11:00-4:45 p.m.

11:00-12:00 p.m.

Results of Patient Focus Group Discussions

Karlynn BrintzenhofeSzoc, PhD

Through the Lens of Patient Partners: Considerations Regarding Accrual of Older Adults to Clinical trials: A Panel Discussion

 Alexis Bakos, PhD, MPH, RN
Patient Partners

 

 

MODERATED SESSIONS

The following 3 sessions are designed to stimulate in-depth discussions of priorities determined by the participants on Day 1 that will inform next steps

Time Topic Presenter/Moderator
12:00-1:00 p.m. Study Design

Heidi Klepin, MD
1:00-2:00 p.m. Infrastructure

William Dale, MD, PhD
2:00-2:30 p.m. BREAK

 
2:30-3:30 p.m. Stakeholder

Supriya Mohile, MD, MS
3:30-4:00 p.m. Plans for Next Phase

Diane St. Germain, RN, MSM
Supriya Mohile, MD, MS