cct-traco-exam

1. Resistance to EGFR tyrosine kinase inhibitors can result from:

(a) EGFR mutations

(b) HER2 amplification

(c) SCLC transformation

(d) all of the above

(e) none of the above

2. Immune checkpoint inhibitors include:

(a) Nivolumab

(b) Erlotinib

(c) Herceptin

(d) all of the above

(e) none of the above

3. HIV attachment and entry is regulated by:

(a) GP120

(b) CD4

(c) CXCR4

(d) all of the above

(e) none of the above

4. Cervical cancer:

(a) is not encoded by L1

(b) is caused by papilloma virus

(c) is best treated with vaccine in adults over 20 years of age

(d) all of the above

(e) none of the above

5. Which cancer has the highest incidence in the world?

(a) Breast cancer

(b) Colorectal cancer

(c) Lymphoma

(d) all of the above

(e) none of the above

6. Tumor suppressor genes can be silenced by:

(a) deacetylation

(b) histone deacetylase inhibitors

(c) methylation

(d) all of the above

(e) none of the above

7. Patient rights are protected by:

(a) Informed consent

(b) FDA

(c) Pharmaceutical companies

(d) all of the above

(e) none of the above

8. Liver tumor growth is altered by:

(a) Gut microbiota

(b) bile acids

(c) Hepatic NKT cells

(d) all of the above

(e) none of the above

9. Small molecule assay considerations include:

(a) High throughput

(b) Instrument availability

(c) Reagents

(d) all of the above

(e) none of the above

10. Cancer health disparities result from:

(a) Health insurance differences

(b) socioeconomic factors

(c) cultural factors

(d) all of the above

(e) none of the above

11. Ovarian cancer:

(a) is frequently detected in stage I

(b) is treated with gefitinib

(c) has a BRCA-1 linked hereditary component

(d) all of the above

(e) none of the above

12. Prostate cancer is treated with:

(a) surgery

(b) radiation

(c) brachytherapy

(d) all of the above

(e) none of the above

13. After radiation therapy cancer cells:

(a) repair DNA

(b) Redistribute

(c) Reoxygenate

(d) all of the above

(e) none of the above

14. Tumors can be imaged with:

(a) MRI

(b) CT

(c) Ultrasound

(d) all of the above

(e) none of the above

15. NSCLC is treated with:

(a) Chemotherapy

(b) Targeted therapy

(c) Immunotherapy

(d) all of the above

(e) none of the above

16. Triple negative breast cancer is treated with:

(a) Herceptin

(b) Immunotherapy

(c) Aromatase inhibitors

(d) all of the above

(e) none of the above

17. Cannabinoids:

(a) reduce neuropathic pain

(b) stimulate cancer growth

(c) cause GI inflammation

(d) all of the above

(e) none of the above

18. Pediatric cancers are associated with:

(a) EGFR mutations

(b) Germline mutations

(c) Somatic mutations

(d) all of the above

(e) none of the above

19. Nanotechnology particles include:

(a) dendrimer

(b) gold nanoshell

(c) quantum dot

(d) all of the above

(e) none of the above

20. Poor cancer prognosis is associated with:

(a) decreased BRCA-1

(b) decreased HIF1a

(c) increased miR-21

(d) all of the above

(e) none of the above

21. CD19 CAR-T cells are used to treat

(a) Non-small cell lung cancer (NSCLC)

(b) Pediatric ALL

(c) Colorectal cancer

(d) all of the above

(e) none of the above

22. Case reports:

(a) do not provide a patient history

(b) do not describe patient treatment

(c) do not include meta analysis

(d) all of the above

(e) none of the above

23. Liquid biopsies can measure:

(a) Circulating tumor cells

(b) Exosomes

(c) ctDNA

(d) all of the above

(e) none of the above

24. Pancreatic cancer is associated with:

(a) pancreatitis

(b) alcohol

(c) UV radiation

(d) all of the above

(e) none of the above

25. Topoisomerase 1

(a) is inhibited by camptothecin

(b) unwinds DNA

(c) is inhibited by indenoisoquinolines

(d) all of the above

(e) none of the above

26. K-RAS is impaired by:

(a) Ftase inhibitors

(b) G12C inhibitors

(c) G12D inhibitors

(d) all of the above

(e) none of the above

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