Emerging Approaches for Tumor Analyses in Epidemiological Studies Course (Instructors)



Maria Teresa Landi, M.D., Ph.D.


Senior Advisor for Genomic Epidemiology

Dr. Landi is a Senior Investigator at Integrative Tumor Epidemiology Branch (ITEB), Division of Cancer Epidemiology and Genetics (DCEG). Her research focuses on understanding tumor etiology and evolution for potential translational applications. She leads large-scale multidisciplinary research projects primarily on genetic and environmental determinants of lung cancer and melanoma, including the Sherlock-Lung study.

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Phuc Hoang, Ph.D.



Dr. Phuc Hoang received his Master in Biochemistry from the University of Oxford and Ph.D. in cancer genetics/bioinformatics from The Institute of Cancer Research, London in 2020. He is currently working on analyzing DNA methylation and Radiology data in the Sherlock-Lung project.


Alyssa Klein



Alyssa Klein received her MS in Bioinformatics from Hood College in May 2020. She works as a bioinformatician to support the Integrative Tumor Epidemiology Branch (ITEB), helping to manage and analyze large genomic databases from epidemiological and clinical studies.


John McElderry



John received his M.Sc in Bioinformatics from Johns Hopkins University in December 2020. He works on the Sherlock Lung project with a current focus on characterizing the lung microbiome and mitochondrial genome in lung cancer.


Jian Sang, Ph.D.


Postdoctoral Fellow

Jian Sang, Ph.D., earned his Ph.D. in bioinformatics from the University of the Chinese Academy of Sciences in 2019. Dr. Sang joined ITEB as a postdoctoral fellow in September 2019 to work with Dr. Landi by deep mining whole genome/exome sequencing data as part of Sherlock Lung.

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Difei Wang, Ph.D.


Bioinformatics Manager

Dr. Difei Wang is the Bioinformatics manager for the Research Analysis Support Group of the Cancer Genomics Research Laboratory (CGR), operated by Leidos Biomedical Research, Inc. for the Division of Cancer Epidemiology and Genetics (DCEG), National Cancer Institute (NCI). He obtained his Ph.D. in Computational Chemistry from the Hong Kong University of Science and Technology. His recent work focuses on analyses of whole transcriptomics, gene fusion, tumor-infiltrating immune cells, mutational signature, GWAS and polygenic risk score, spatial genomics, single-cell sequencing, and PacBio long reads sequencing.


Wendy Wong, Ph.D.


Senior Biomedical Research Scientist

Dr. Wendy Wong received her M.S. and Ph.D. in biometry (biological statistics) from Cornell University, where she developed statistical models of the processes of molecular evolution using sequence data. She has a B.S. in genetics, bacteriology, mathematics, computer sciences and statistics from the University of Wisconsin - Madison.

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Tongwu Zhang, Ph.D.


Staff Scientist

Dr. Tongwu Zhang received his Ph.D. in bioinformatics from Zhejiang University, China, in June 2012. Dr. Zhang’s research focuses on analyzing, integrating, and interpreting multi-omics data for both cancer genomic and genetic studies. He leads the genomic analyses and develops new bioinformatics tools and pipelines for Sherlock-Lung, a study that aims to elucidate the etiology of lung cancer in never smokers (LCINS).

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Wei Zhao, Ph.D.


Research Fellow

Dr. Wei Zhao earned her Ph.D. in bioinformatics from the University of North Carolina at Chapel Hill in 2014 researching genomic and clinical heterogeneity of breast cancer using deep- sequencing and microarray. She joined ITEB in 2018 working with Dr. Landi on Sherlock Lung. Her current research focuses on transcriptomics and tumor microenvironment.

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